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Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles

The aim of this study was to investigate whether maternal age had an effect on the birthweight of singletons delivered from frozen-thawed blastocyst transfer (FBT) cycles. A total of 1203 FBT cycles occurring between July 2011 and June 2021 at a single centre were retrospectively analysed. Based on...

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Autores principales: Wang, Xue, Xiao, YaLing, Tao, Tao, Xiong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368368/
https://www.ncbi.nlm.nih.gov/pubmed/37497353
http://dx.doi.org/10.3389/fendo.2023.1195256
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author Wang, Xue
Xiao, YaLing
Tao, Tao
Xiong, Wei
author_facet Wang, Xue
Xiao, YaLing
Tao, Tao
Xiong, Wei
author_sort Wang, Xue
collection PubMed
description The aim of this study was to investigate whether maternal age had an effect on the birthweight of singletons delivered from frozen-thawed blastocyst transfer (FBT) cycles. A total of 1203 FBT cycles occurring between July 2011 and June 2021 at a single centre were retrospectively analysed. Based on the maternal age at FBT, the patients were divided into four groups: <30, 30–34, 35−37, and ≥38 years of age. Main outcomes measured included singleton birthweights, preterm births, large-for-gestational-age (LGA) and small-for-gestational-age (SGA) live births among the groups. There was no significant difference in birth weight among the four groups, while the highest birth weight was found in the <30 years group. The incidence of very preterm births and very low birth weights demonstrated an increasing trend with age; on the contrary, the incidence of preterm births, low birth weight (LBW), high birth weight and LGA and SGA live births gradually decreased with increasing age, but these differences were not statistically significant among groups (P>0.05, respectively). Although the proportion of females was lower than that of males, the difference was not statistically significant among the groups. After adjusting for possible confounders, maternal age was found to have no effect on adverse neonatal outcomes in the regression analyses (P>0.05). Birthweight in singleton births from FBT was not affected by maternal age.
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spelling pubmed-103683682023-07-26 Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles Wang, Xue Xiao, YaLing Tao, Tao Xiong, Wei Front Endocrinol (Lausanne) Endocrinology The aim of this study was to investigate whether maternal age had an effect on the birthweight of singletons delivered from frozen-thawed blastocyst transfer (FBT) cycles. A total of 1203 FBT cycles occurring between July 2011 and June 2021 at a single centre were retrospectively analysed. Based on the maternal age at FBT, the patients were divided into four groups: <30, 30–34, 35−37, and ≥38 years of age. Main outcomes measured included singleton birthweights, preterm births, large-for-gestational-age (LGA) and small-for-gestational-age (SGA) live births among the groups. There was no significant difference in birth weight among the four groups, while the highest birth weight was found in the <30 years group. The incidence of very preterm births and very low birth weights demonstrated an increasing trend with age; on the contrary, the incidence of preterm births, low birth weight (LBW), high birth weight and LGA and SGA live births gradually decreased with increasing age, but these differences were not statistically significant among groups (P>0.05, respectively). Although the proportion of females was lower than that of males, the difference was not statistically significant among the groups. After adjusting for possible confounders, maternal age was found to have no effect on adverse neonatal outcomes in the regression analyses (P>0.05). Birthweight in singleton births from FBT was not affected by maternal age. Frontiers Media S.A. 2023-07-10 /pmc/articles/PMC10368368/ /pubmed/37497353 http://dx.doi.org/10.3389/fendo.2023.1195256 Text en Copyright © 2023 Wang, Xiao, Tao and Xiong https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Wang, Xue
Xiao, YaLing
Tao, Tao
Xiong, Wei
Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles
title Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles
title_full Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles
title_fullStr Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles
title_full_unstemmed Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles
title_short Influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles
title_sort influence of maternal age on the birthweight of infants delivered from frozen-thawed blastocyst transfer cycles
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368368/
https://www.ncbi.nlm.nih.gov/pubmed/37497353
http://dx.doi.org/10.3389/fendo.2023.1195256
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