Cargando…
Lipid homeostasis is essential for a maximal ER stress response
Changes in lipid metabolism are associated with aging and age-related diseases, including proteopathies. The endoplasmic reticulum (ER) is uniquely a major hub for protein and lipid synthesis, making its function essential for both protein and lipid homeostasis. However, it is less clear how lipid m...
Autores principales: | Garcia, Gilberto, Zhang, Hanlin, Moreno, Sophia, Tsui, C Kimberly, Webster, Brant Michael, Higuchi-Sanabria, Ryo, Dillin, Andrew |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368420/ https://www.ncbi.nlm.nih.gov/pubmed/37489956 http://dx.doi.org/10.7554/eLife.83884 |
Ejemplares similares
-
Beyond the cell factory: Homeostatic regulation of and by the UPR(ER)
por: Metcalf, Melissa G., et al.
Publicado: (2020) -
ER-Phagy: A New Regulator of ER Homeostasis
por: Yang, Ming, et al.
Publicado: (2021) -
Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration
por: Ye, Risheng, et al.
Publicado: (2014) -
A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress
por: Stephani, Madlen, et al.
Publicado: (2020) -
Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets
por: Zoni, Valeria, et al.
Publicado: (2021)