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Effect of PCC on Thrombin Generation among Patients on Factor Xa Inhibitors with Major Bleeding or Needing Urgent Surgery (GAUGE): Design and Rationale

Background  Direct factor Xa inhibitors (FXaIs) account for most oral anticoagulant use and FXaI-associated bleeding events are common. Clinicians have variable national and regional access to specific FXaI reversal agents such as andexanet alfa. Many centers have adopted the use of prothrombin comp...

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Detalles Bibliográficos
Autores principales: Shaw, Joseph R., Unachukwu, Ubabuko, Cyr, Joseph, Siegal, Deborah M., Castellucci, Lana A., Dreden, Patrick Van, Dowlatshahi, Dar, Buyukdere, Hakan, Ramsay, Timothy, Carrier, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368490/
https://www.ncbi.nlm.nih.gov/pubmed/37497426
http://dx.doi.org/10.1055/s-0043-1771300