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Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease

PURPOSE: Septic arthritis of the native hip joint (SANH) is an uncommon surgical and medical emergency with few reports. The aim of this study was to determine predictors of return to theatre (RTT), complications and mortality. METHODS: Patients with SANH were identified from January 2009 to June 20...

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Autores principales: Kim, Byungseob, Boukebous, Baptiste, White, Douglas, Baker, Joseph F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368560/
https://www.ncbi.nlm.nih.gov/pubmed/36710273
http://dx.doi.org/10.1007/s00590-023-03477-2
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author Kim, Byungseob
Boukebous, Baptiste
White, Douglas
Baker, Joseph F.
author_facet Kim, Byungseob
Boukebous, Baptiste
White, Douglas
Baker, Joseph F.
author_sort Kim, Byungseob
collection PubMed
description PURPOSE: Septic arthritis of the native hip joint (SANH) is an uncommon surgical and medical emergency with few reports. The aim of this study was to determine predictors of return to theatre (RTT), complications and mortality. METHODS: Patients with SANH were identified from January 2009 to June 2022; 50 patients and three subgroups were identified: Pyogenic (surgical washout without systemic inflammatory disease), Systemic (surgical washout with SIDs) and patients managed non-surgically. Patterns of these groups were assessed with a principal component analysis. The cumulative incidences for death, any complication and RTT for repeat washout were calculated. The predictive variables associated with outcomes were selected with univariable models and then incorporated in multivariable CoxPH regressions. RESULTS: The 1-year cumulative incidence was 14% for mortality and 48.5% for any complication. Amongst patients managed surgically, 1-year risk of RTT was 46% in Pyogenic subgroup and 21% in Systemic subgroup. Systemic subgroup had lower complications and RTT and higher rate of sterile aspirate, compared to Pyogenic. Charlson comorbidity index (CCI) (HR = 1.41, P value = 0.03), preoperative albumin (HR = 0.81, P value = 0.009) and preoperative haemoglobin (HR = 0.95, P value = 0.02) were significantly associated with 1-year mortality. Time between symptom onset and admission > 7 days (HR = 3.15, P value = 0.042), preoperative Hb (HR = 1.05, P value = 0.016), socioeconomic deprivation (HR = 1.18, P value = 0.04) and Systemic subgroup (HR = 0.25, P value = 0.04) were significantly associated with RTT. CONCLUSION: Mortality was well predicted by the usual parameters including CCI, albumin, but also low haemoglobin. Patients presenting in a delayed fashion were more likely to have multiple lavages.
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spelling pubmed-103685602023-07-27 Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease Kim, Byungseob Boukebous, Baptiste White, Douglas Baker, Joseph F. Eur J Orthop Surg Traumatol Original Article PURPOSE: Septic arthritis of the native hip joint (SANH) is an uncommon surgical and medical emergency with few reports. The aim of this study was to determine predictors of return to theatre (RTT), complications and mortality. METHODS: Patients with SANH were identified from January 2009 to June 2022; 50 patients and three subgroups were identified: Pyogenic (surgical washout without systemic inflammatory disease), Systemic (surgical washout with SIDs) and patients managed non-surgically. Patterns of these groups were assessed with a principal component analysis. The cumulative incidences for death, any complication and RTT for repeat washout were calculated. The predictive variables associated with outcomes were selected with univariable models and then incorporated in multivariable CoxPH regressions. RESULTS: The 1-year cumulative incidence was 14% for mortality and 48.5% for any complication. Amongst patients managed surgically, 1-year risk of RTT was 46% in Pyogenic subgroup and 21% in Systemic subgroup. Systemic subgroup had lower complications and RTT and higher rate of sterile aspirate, compared to Pyogenic. Charlson comorbidity index (CCI) (HR = 1.41, P value = 0.03), preoperative albumin (HR = 0.81, P value = 0.009) and preoperative haemoglobin (HR = 0.95, P value = 0.02) were significantly associated with 1-year mortality. Time between symptom onset and admission > 7 days (HR = 3.15, P value = 0.042), preoperative Hb (HR = 1.05, P value = 0.016), socioeconomic deprivation (HR = 1.18, P value = 0.04) and Systemic subgroup (HR = 0.25, P value = 0.04) were significantly associated with RTT. CONCLUSION: Mortality was well predicted by the usual parameters including CCI, albumin, but also low haemoglobin. Patients presenting in a delayed fashion were more likely to have multiple lavages. Springer Paris 2023-01-29 2023 /pmc/articles/PMC10368560/ /pubmed/36710273 http://dx.doi.org/10.1007/s00590-023-03477-2 Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Kim, Byungseob
Boukebous, Baptiste
White, Douglas
Baker, Joseph F.
Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease
title Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease
title_full Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease
title_fullStr Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease
title_full_unstemmed Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease
title_short Septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease
title_sort septic arthritis of the native hip joint: a multi-pattern, multi-outcome disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368560/
https://www.ncbi.nlm.nih.gov/pubmed/36710273
http://dx.doi.org/10.1007/s00590-023-03477-2
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