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Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation

Pulmonary extra‐nodal marginal zone B‐cell lymphoma, also known as extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma, is rare among all non‐Hodgkin lymphomas and generally among all pulmonary malignancies. We present a 46‐year‐old lady with persistent right lower lung consolidation despi...

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Autores principales: Kou, Lily, Huan, Nai‐Chien, Nyanti, Larry Ellee, Chin, Jiunn Sheng, Mohamad, Nor Bahiyyah, Ramarmuty, Hema Yamini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368649/
https://www.ncbi.nlm.nih.gov/pubmed/37501686
http://dx.doi.org/10.1002/rcr2.1197
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author Kou, Lily
Huan, Nai‐Chien
Nyanti, Larry Ellee
Chin, Jiunn Sheng
Mohamad, Nor Bahiyyah
Ramarmuty, Hema Yamini
author_facet Kou, Lily
Huan, Nai‐Chien
Nyanti, Larry Ellee
Chin, Jiunn Sheng
Mohamad, Nor Bahiyyah
Ramarmuty, Hema Yamini
author_sort Kou, Lily
collection PubMed
description Pulmonary extra‐nodal marginal zone B‐cell lymphoma, also known as extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma, is rare among all non‐Hodgkin lymphomas and generally among all pulmonary malignancies. We present a 46‐year‐old lady with persistent right lower lung consolidation despite earlier treatment efforts with intravenous antibiotics for community acquired pneumonia. Apart from initial presentation with a short 3‐day history of fever, cough and shortness of breath, she had remained largely asymptomatic throughout the follow‐up period. Flexible bronchoscopy done ruled out infectious aetiologies but transbronchial lung biopsies showed atypical lymphocytes. A computed tomography guided core biopsy of her right lung consolidation was subsequently performed, confirming a diagnosis of pulmonary MALT lymphoma. She was promptly referred to the haematology team for further management and commencement of chemotherapy. Pulmonary MALT lymphoma, albeit uncommon and often follows a relatively indolent cause, should be considered as a differential diagnosis among patients with persistent lung consolidation.
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spelling pubmed-103686492023-07-27 Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation Kou, Lily Huan, Nai‐Chien Nyanti, Larry Ellee Chin, Jiunn Sheng Mohamad, Nor Bahiyyah Ramarmuty, Hema Yamini Respirol Case Rep Case Reports Pulmonary extra‐nodal marginal zone B‐cell lymphoma, also known as extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma, is rare among all non‐Hodgkin lymphomas and generally among all pulmonary malignancies. We present a 46‐year‐old lady with persistent right lower lung consolidation despite earlier treatment efforts with intravenous antibiotics for community acquired pneumonia. Apart from initial presentation with a short 3‐day history of fever, cough and shortness of breath, she had remained largely asymptomatic throughout the follow‐up period. Flexible bronchoscopy done ruled out infectious aetiologies but transbronchial lung biopsies showed atypical lymphocytes. A computed tomography guided core biopsy of her right lung consolidation was subsequently performed, confirming a diagnosis of pulmonary MALT lymphoma. She was promptly referred to the haematology team for further management and commencement of chemotherapy. Pulmonary MALT lymphoma, albeit uncommon and often follows a relatively indolent cause, should be considered as a differential diagnosis among patients with persistent lung consolidation. John Wiley & Sons, Ltd 2023-07-25 /pmc/articles/PMC10368649/ /pubmed/37501686 http://dx.doi.org/10.1002/rcr2.1197 Text en © 2023 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Kou, Lily
Huan, Nai‐Chien
Nyanti, Larry Ellee
Chin, Jiunn Sheng
Mohamad, Nor Bahiyyah
Ramarmuty, Hema Yamini
Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation
title Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation
title_full Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation
title_fullStr Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation
title_full_unstemmed Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation
title_short Pulmonary extra‐nodal mucosa‐associated lymphoid tissue (MALT) lymphoma: A rare cause of persistent lung consolidation
title_sort pulmonary extra‐nodal mucosa‐associated lymphoid tissue (malt) lymphoma: a rare cause of persistent lung consolidation
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368649/
https://www.ncbi.nlm.nih.gov/pubmed/37501686
http://dx.doi.org/10.1002/rcr2.1197
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