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A role of splenic heme biosynthesis pathway in the persistent prophylactic actions of arketamine in lipopolysaccharide-treated mice

Relapse is common in remitted patients with major depressive disorder (MDD). Arketamine, an (R)-enantiomer of ketamine, has persistent prophylactic actions in an inflammatory model of depression. However, the precise mechanisms underlying these prophylactic actions remain unknown. Given the role of...

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Detalles Bibliográficos
Autores principales:	Ma, Li, Wang, Long, Qu, Youge, Wan, Xiayun, Hashimoto, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368680/ https://www.ncbi.nlm.nih.gov/pubmed/37491335 http://dx.doi.org/10.1038/s41398-023-02564-6

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