Circular RNA encoded MET variant promotes glioblastoma tumorigenesis

Activated by its single ligand, hepatocyte growth factor (HGF), the receptor tyrosine kinase MET is pivotal in promoting glioblastoma (GBM) stem cell self-renewal, invasiveness and tumorigenicity. Nevertheless, HGF/MET-targeted therapy has shown limited clinical benefits in GBM patients, suggesting...

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Detalles Bibliográficos
Autores principales: Zhong, Jian, Wu, Xujia, Gao, Yixin, Chen, Junju, Zhang, Maolei, Zhou, Huangkai, Yang, Jia, Xiao, Feizhe, Yang, Xuesong, Huang, Nunu, Qi, Haoyue, Wang, Xiuxing, Bai, Fan, Shi, Yu, Zhang, Nu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368723/
https://www.ncbi.nlm.nih.gov/pubmed/37491377
http://dx.doi.org/10.1038/s41467-023-40212-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368723/
https://www.ncbi.nlm.nih.gov/pubmed/37491377
http://dx.doi.org/10.1038/s41467-023-40212-1

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