Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice

Hypercholesterolemia and vascular inflammation are key interconnected contributors to the pathogenesis of atherosclerosis. How hypercholesterolemia initiates vascular inflammation is poorly understood. Here we show in male mice that hypercholesterolemia-driven endothelial activation, monocyte recrui...

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Detalles Bibliográficos
Autores principales: Yu, Liming, Xu, Lin, Chu, Haiyan, Peng, Jun, Sacharidou, Anastasia, Hsieh, Hsi-hsien, Weinstock, Ada, Khan, Sohaib, Ma, Liqian, Durán, José Gabriel Barcia, McDonald, Jeffrey, Nelson, Erik R., Park, Sunghee, McDonnell, Donald P., Moore, Kathryn J., Huang, Lily Jun-shen, Fisher, Edward A., Mineo, Chieko, Huang, Linzhang, Shaul, Philip W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368733/
https://www.ncbi.nlm.nih.gov/pubmed/37491347
http://dx.doi.org/10.1038/s41467-023-39586-z

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