Ezh2 emerges as an epigenetic checkpoint regulator during monocyte differentiation limiting cardiac dysfunction post-MI

Epigenetic regulation of histone H3K27 methylation has recently emerged as a key step during alternative immunoregulatory M2-like macrophage polarization; known to impact cardiac repair after Myocardial Infarction (MI). We hypothesized that EZH2, responsible for H3K27 methylation, could act as an ep...

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Detalles Bibliográficos
Autores principales: Rondeaux, Julie, Groussard, Déborah, Renet, Sylvanie, Tardif, Virginie, Dumesnil, Anaïs, Chu, Alphonse, Di Maria, Léa, Lemarcis, Théo, Valet, Manon, Henry, Jean-Paul, Badji, Zina, Vézier, Claire, Béziau-Gasnier, Delphine, Neele, Annette E., de Winther, Menno P. J., Guerrot, Dominique, Brand, Marjorie, Richard, Vincent, Durand, Eric, Brakenhielm, Ebba, Fraineau, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368741/
https://www.ncbi.nlm.nih.gov/pubmed/37491334
http://dx.doi.org/10.1038/s41467-023-40186-0

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