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Loss of p53 enhances the tumor-initiating potential and drug resistance of clonogenic multiple myeloma cells
Tumor relapse and drug resistance are major factors that limit the curability of multiple myeloma (MM). New regimens have improved overall MM survival rates, but patients with high-risk features continue to have inferior outcomes. Chromosome 17p13 deletion (del17p) that includes the loss of the TP53...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society of Hematology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368840/ https://www.ncbi.nlm.nih.gov/pubmed/37042949 http://dx.doi.org/10.1182/bloodadvances.2022009387 |