FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro

The differentiation of human pluripotent stem cells into the SOX17(+) definitive endoderm (DE) germ layer is important for generating tissues for regenerative medicine. Multiple developmental and stem cell studies have demonstrated that Activin/Nodal signaling is the primary driver of definitive end...

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Detalles Bibliográficos
Autores principales: Lau, Hwee Hui, Amirruddin, Nur Shabrina, Loo, Larry Sai Weng, Chan, Jun Wei, Iich, Elhadi, Krishnan, Vidhya Gomathi, Hoon, Shawn, Teo, Adrian Kee Keong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368912/
https://www.ncbi.nlm.nih.gov/pubmed/37502260
http://dx.doi.org/10.1016/j.isci.2023.107265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368912/
https://www.ncbi.nlm.nih.gov/pubmed/37502260
http://dx.doi.org/10.1016/j.isci.2023.107265

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