Cargando…
Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report
This case report presents an 82-year-old woman with decreased visual acuity. Clinical and multimodal evaluation revealed an elevated macular lesion with choroidal thickening. Fluorescein angiography and optical coherence tomography (OCT) showed characteristic patterns of choroidal metastasis. Thorac...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369012/ https://www.ncbi.nlm.nih.gov/pubmed/37503465 http://dx.doi.org/10.7759/cureus.40955 |
_version_ | 1785077665834729472 |
---|---|
author | Reis da Silva, Alexandre Basto, Rita Correia Barbosa, Renato Viana, Ana Rita Teixeira, Carla |
author_facet | Reis da Silva, Alexandre Basto, Rita Correia Barbosa, Renato Viana, Ana Rita Teixeira, Carla |
author_sort | Reis da Silva, Alexandre |
collection | PubMed |
description | This case report presents an 82-year-old woman with decreased visual acuity. Clinical and multimodal evaluation revealed an elevated macular lesion with choroidal thickening. Fluorescein angiography and optical coherence tomography (OCT) showed characteristic patterns of choroidal metastasis. Thoracic CT scan confirmed a nodular mass in the right hilus, suggesting bronchogenic neoplastic process. A pleural biopsy demonstrated malignant neoplasia with characteristics of adenocarcinoma, and immunohistochemistry was positive for thyroid transcription factor 1 (TTF-1). These findings emphasize the critical role of ophthalmological examinations in early detection and intervention, as choroidal tissue is highly susceptible to metastasis, particularly from breast and lung cancers. Additionally, the poor prognosis associated with metastatic lung cancer underscores the urgency for prompt action. |
format | Online Article Text |
id | pubmed-10369012 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-103690122023-07-27 Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report Reis da Silva, Alexandre Basto, Rita Correia Barbosa, Renato Viana, Ana Rita Teixeira, Carla Cureus Ophthalmology This case report presents an 82-year-old woman with decreased visual acuity. Clinical and multimodal evaluation revealed an elevated macular lesion with choroidal thickening. Fluorescein angiography and optical coherence tomography (OCT) showed characteristic patterns of choroidal metastasis. Thoracic CT scan confirmed a nodular mass in the right hilus, suggesting bronchogenic neoplastic process. A pleural biopsy demonstrated malignant neoplasia with characteristics of adenocarcinoma, and immunohistochemistry was positive for thyroid transcription factor 1 (TTF-1). These findings emphasize the critical role of ophthalmological examinations in early detection and intervention, as choroidal tissue is highly susceptible to metastasis, particularly from breast and lung cancers. Additionally, the poor prognosis associated with metastatic lung cancer underscores the urgency for prompt action. Cureus 2023-06-25 /pmc/articles/PMC10369012/ /pubmed/37503465 http://dx.doi.org/10.7759/cureus.40955 Text en Copyright © 2023, Reis da Silva et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Ophthalmology Reis da Silva, Alexandre Basto, Rita Correia Barbosa, Renato Viana, Ana Rita Teixeira, Carla Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report |
title | Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report |
title_full | Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report |
title_fullStr | Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report |
title_full_unstemmed | Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report |
title_short | Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report |
title_sort | choroidal metastasis as the initial presentation of lung cancer: a case report |
topic | Ophthalmology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369012/ https://www.ncbi.nlm.nih.gov/pubmed/37503465 http://dx.doi.org/10.7759/cureus.40955 |
work_keys_str_mv | AT reisdasilvaalexandre choroidalmetastasisastheinitialpresentationoflungcanceracasereport AT bastorita choroidalmetastasisastheinitialpresentationoflungcanceracasereport AT correiabarbosarenato choroidalmetastasisastheinitialpresentationoflungcanceracasereport AT vianaanarita choroidalmetastasisastheinitialpresentationoflungcanceracasereport AT teixeiracarla choroidalmetastasisastheinitialpresentationoflungcanceracasereport |