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Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report

This case report presents an 82-year-old woman with decreased visual acuity. Clinical and multimodal evaluation revealed an elevated macular lesion with choroidal thickening. Fluorescein angiography and optical coherence tomography (OCT) showed characteristic patterns of choroidal metastasis. Thorac...

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Autores principales: Reis da Silva, Alexandre, Basto, Rita, Correia Barbosa, Renato, Viana, Ana Rita, Teixeira, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369012/
https://www.ncbi.nlm.nih.gov/pubmed/37503465
http://dx.doi.org/10.7759/cureus.40955
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author Reis da Silva, Alexandre
Basto, Rita
Correia Barbosa, Renato
Viana, Ana Rita
Teixeira, Carla
author_facet Reis da Silva, Alexandre
Basto, Rita
Correia Barbosa, Renato
Viana, Ana Rita
Teixeira, Carla
author_sort Reis da Silva, Alexandre
collection PubMed
description This case report presents an 82-year-old woman with decreased visual acuity. Clinical and multimodal evaluation revealed an elevated macular lesion with choroidal thickening. Fluorescein angiography and optical coherence tomography (OCT) showed characteristic patterns of choroidal metastasis. Thoracic CT scan confirmed a nodular mass in the right hilus, suggesting bronchogenic neoplastic process. A pleural biopsy demonstrated malignant neoplasia with characteristics of adenocarcinoma, and immunohistochemistry was positive for thyroid transcription factor 1 (TTF-1). These findings emphasize the critical role of ophthalmological examinations in early detection and intervention, as choroidal tissue is highly susceptible to metastasis, particularly from breast and lung cancers. Additionally, the poor prognosis associated with metastatic lung cancer underscores the urgency for prompt action.
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spelling pubmed-103690122023-07-27 Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report Reis da Silva, Alexandre Basto, Rita Correia Barbosa, Renato Viana, Ana Rita Teixeira, Carla Cureus Ophthalmology This case report presents an 82-year-old woman with decreased visual acuity. Clinical and multimodal evaluation revealed an elevated macular lesion with choroidal thickening. Fluorescein angiography and optical coherence tomography (OCT) showed characteristic patterns of choroidal metastasis. Thoracic CT scan confirmed a nodular mass in the right hilus, suggesting bronchogenic neoplastic process. A pleural biopsy demonstrated malignant neoplasia with characteristics of adenocarcinoma, and immunohistochemistry was positive for thyroid transcription factor 1 (TTF-1). These findings emphasize the critical role of ophthalmological examinations in early detection and intervention, as choroidal tissue is highly susceptible to metastasis, particularly from breast and lung cancers. Additionally, the poor prognosis associated with metastatic lung cancer underscores the urgency for prompt action. Cureus 2023-06-25 /pmc/articles/PMC10369012/ /pubmed/37503465 http://dx.doi.org/10.7759/cureus.40955 Text en Copyright © 2023, Reis da Silva et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Reis da Silva, Alexandre
Basto, Rita
Correia Barbosa, Renato
Viana, Ana Rita
Teixeira, Carla
Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report
title Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report
title_full Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report
title_fullStr Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report
title_full_unstemmed Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report
title_short Choroidal Metastasis as the Initial Presentation of Lung Cancer: A Case Report
title_sort choroidal metastasis as the initial presentation of lung cancer: a case report
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369012/
https://www.ncbi.nlm.nih.gov/pubmed/37503465
http://dx.doi.org/10.7759/cureus.40955
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