Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis

An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch th...

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Autores principales: Akiki, Elias, Ahmad, Ali, El-Am, Edward A., Casanegra, Ana I., Klarich, Kyle W., Kurmann, Reto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369060/
https://www.ncbi.nlm.nih.gov/pubmed/37502185
http://dx.doi.org/10.3389/fcvm.2023.1208190
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author Akiki, Elias
Ahmad, Ali
El-Am, Edward A.
Casanegra, Ana I.
Klarich, Kyle W.
Kurmann, Reto
author_facet Akiki, Elias
Ahmad, Ali
El-Am, Edward A.
Casanegra, Ana I.
Klarich, Kyle W.
Kurmann, Reto
author_sort Akiki, Elias
collection PubMed
description An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy.
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spelling pubmed-103690602023-07-27 Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis Akiki, Elias Ahmad, Ali El-Am, Edward A. Casanegra, Ana I. Klarich, Kyle W. Kurmann, Reto Front Cardiovasc Med Cardiovascular Medicine An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy. Frontiers Media S.A. 2023-07-12 /pmc/articles/PMC10369060/ /pubmed/37502185 http://dx.doi.org/10.3389/fcvm.2023.1208190 Text en © 2023 Akiki, Ahmad, El-Am, Casanegra, Klarich and Kurmann. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Akiki, Elias
Ahmad, Ali
El-Am, Edward A.
Casanegra, Ana I.
Klarich, Kyle W.
Kurmann, Reto
Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis
title Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis
title_full Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis
title_fullStr Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis
title_full_unstemmed Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis
title_short Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis
title_sort case report: new is not always better: treatment of non-bacterial thrombotic endocarditis
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369060/
https://www.ncbi.nlm.nih.gov/pubmed/37502185
http://dx.doi.org/10.3389/fcvm.2023.1208190
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