Transplanting Human Neural Stem Cells with ≈50% Reduction of SOX9 Gene Dosage Promotes Tissue Repair and Functional Recovery from Severe Spinal Cord Injury

Neural stem cells (NSCs) derived from human pluripotent stem cells (hPSCs) are considered a major cell source for reconstructing damaged neural circuitry and enabling axonal regeneration. However, the microenvironment at the site of spinal cord injury (SCI) and inadequate intrinsic factors limit the...

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Detalles Bibliográficos
Autores principales: Liu, Jessica Aijia, Tam, Kin Wai, Chen, Yong Long, Feng, Xianglan, Chan, Christy Wing Lam, Lo, Amos Lok Hang, Wu, Kenneth Lap‐Kei, Hui, Man‐Ning, Wu, Ming‐Hoi, Chan, Ken Kwok‐Keung, Cheung, May Pui Lai, Cheung, Chi Wai, Shum, Daisy Kwok‐Yan, Chan, Ying‐Shing, Cheung, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369238/
https://www.ncbi.nlm.nih.gov/pubmed/37296073
http://dx.doi.org/10.1002/advs.202205804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369238/
https://www.ncbi.nlm.nih.gov/pubmed/37296073
http://dx.doi.org/10.1002/advs.202205804

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