An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity

Over the last decade, adipose‐derived stem cells (ADSCs) have attracted increasing attention in the field of regenerative medicine. ADSCs appear to be the most advantageous cell type for regenerative therapies owing to their easy accessibility, multipotency, and active paracrine activity. This revie...

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Autores principales: Qin, Yi, Ge, Gaoran, Yang, Peng, Wang, Liangliang, Qiao, Yusen, Pan, Guoqing, Yang, Huilin, Bai, Jiaxiang, Cui, Wenguo, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369252/
https://www.ncbi.nlm.nih.gov/pubmed/37162248
http://dx.doi.org/10.1002/advs.202207334
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author Qin, Yi
Ge, Gaoran
Yang, Peng
Wang, Liangliang
Qiao, Yusen
Pan, Guoqing
Yang, Huilin
Bai, Jiaxiang
Cui, Wenguo
Geng, Dechun
author_facet Qin, Yi
Ge, Gaoran
Yang, Peng
Wang, Liangliang
Qiao, Yusen
Pan, Guoqing
Yang, Huilin
Bai, Jiaxiang
Cui, Wenguo
Geng, Dechun
author_sort Qin, Yi
collection PubMed
description Over the last decade, adipose‐derived stem cells (ADSCs) have attracted increasing attention in the field of regenerative medicine. ADSCs appear to be the most advantageous cell type for regenerative therapies owing to their easy accessibility, multipotency, and active paracrine activity. This review highlights current challenges in translating ADSC‐based therapies into clinical settings and discusses novel strategies to overcome the limitations of ADSCs. To further establish ADSC‐based therapies as an emerging platform for regenerative medicine, this review also provides an update on the advancements in this field, including fat grafting, wound healing, bone regeneration, skeletal muscle repair, tendon reconstruction, cartilage regeneration, cardiac repair, and nerve regeneration. ADSC‐based therapies are expected to be more tissue‐specific and increasingly important in regenerative medicine.
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spelling pubmed-103692522023-07-27 An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity Qin, Yi Ge, Gaoran Yang, Peng Wang, Liangliang Qiao, Yusen Pan, Guoqing Yang, Huilin Bai, Jiaxiang Cui, Wenguo Geng, Dechun Adv Sci (Weinh) Reviews Over the last decade, adipose‐derived stem cells (ADSCs) have attracted increasing attention in the field of regenerative medicine. ADSCs appear to be the most advantageous cell type for regenerative therapies owing to their easy accessibility, multipotency, and active paracrine activity. This review highlights current challenges in translating ADSC‐based therapies into clinical settings and discusses novel strategies to overcome the limitations of ADSCs. To further establish ADSC‐based therapies as an emerging platform for regenerative medicine, this review also provides an update on the advancements in this field, including fat grafting, wound healing, bone regeneration, skeletal muscle repair, tendon reconstruction, cartilage regeneration, cardiac repair, and nerve regeneration. ADSC‐based therapies are expected to be more tissue‐specific and increasingly important in regenerative medicine. John Wiley and Sons Inc. 2023-05-10 /pmc/articles/PMC10369252/ /pubmed/37162248 http://dx.doi.org/10.1002/advs.202207334 Text en © 2023 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Qin, Yi
Ge, Gaoran
Yang, Peng
Wang, Liangliang
Qiao, Yusen
Pan, Guoqing
Yang, Huilin
Bai, Jiaxiang
Cui, Wenguo
Geng, Dechun
An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity
title An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity
title_full An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity
title_fullStr An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity
title_full_unstemmed An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity
title_short An Update on Adipose‐Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity
title_sort update on adipose‐derived stem cells for regenerative medicine: where challenge meets opportunity
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369252/
https://www.ncbi.nlm.nih.gov/pubmed/37162248
http://dx.doi.org/10.1002/advs.202207334
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