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In Situ Vaccination with Mitochondria‐Targeting Immunogenic Death Inducer Elicits CD8(+) T Cell‐Dependent Antitumor Immunity to Boost Tumor Immunotherapy
In situ vaccination can elicit systemic antitumor immunity to potentiate immune checkpoint blockade (ICB) in poorly immunogenic tumors. Herein, an immunogenic cell death (ICD) inducer for in situ vaccination, which is based on a mitochondria‐targeting modification of fenofibric acid (FFa), a lipid‐l...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369267/ https://www.ncbi.nlm.nih.gov/pubmed/37127892 http://dx.doi.org/10.1002/advs.202300286 |