In Situ Vaccination with Mitochondria‐Targeting Immunogenic Death Inducer Elicits CD8(+) T Cell‐Dependent Antitumor Immunity to Boost Tumor Immunotherapy

In situ vaccination can elicit systemic antitumor immunity to potentiate immune checkpoint blockade (ICB) in poorly immunogenic tumors. Herein, an immunogenic cell death (ICD) inducer for in situ vaccination, which is based on a mitochondria‐targeting modification of fenofibric acid (FFa), a lipid‐l...

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Detalles Bibliográficos
Autores principales: Wang, Yuxiang, Wang, Weiran, Gu, Rong, Chen, Jing, Chen, Qian, Lin, Tingsheng, Wu, Jinhui, Hu, Yiqiao, Yuan, Ahu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369267/
https://www.ncbi.nlm.nih.gov/pubmed/37127892
http://dx.doi.org/10.1002/advs.202300286

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