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Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report

INTRODUCTION AND IMPORTANCE: Follicular thyroid carcinoma (FTC) exhibits the ability to metastasize hematogenously to distant organs. Spinal metastasis is an unusual site for metastasis that even when it does, spinal metastasis manifests late in the course of the disease and is frequently linked to...

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Autores principales: Njoum, Yumna, Abu-Hilal, Lila H., Barghouthi, Duha, Alshawwa, Khaled, AbuKeshek, Tawfiq, Maree, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369476/
https://www.ncbi.nlm.nih.gov/pubmed/37481973
http://dx.doi.org/10.1016/j.ijscr.2023.108541
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author Njoum, Yumna
Abu-Hilal, Lila H.
Barghouthi, Duha
Alshawwa, Khaled
AbuKeshek, Tawfiq
Maree, Mohammed
author_facet Njoum, Yumna
Abu-Hilal, Lila H.
Barghouthi, Duha
Alshawwa, Khaled
AbuKeshek, Tawfiq
Maree, Mohammed
author_sort Njoum, Yumna
collection PubMed
description INTRODUCTION AND IMPORTANCE: Follicular thyroid carcinoma (FTC) exhibits the ability to metastasize hematogenously to distant organs. Spinal metastasis is an unusual site for metastasis that even when it does, spinal metastasis manifests late in the course of the disease and is frequently linked to advanced disease and a bad prognosis. Until 2019, the literature only showed 29 cases of FTC with spinal metastasis as the first presenting feature. CASE PRESENTATION: We present a case of a 67-year-old female who presented with an acute onset of severe neurological deficit that ended up bedridden. Magnetic resonance imaging of the spine revealed a spinal lesion causing severe spinal cord compression. Urgent surgical decompression was performed, and the histopathology confirmed metastatic FTC. Subsequent comprehensive evaluation, unveiled a primary thyroid tumor. CLINICAL DISCUSSION: FTC accounts for 1 % of all malignancies, Therefore, regardless of how irrelevant symptoms may appear at first, it is important to understand all risk factors, screening recommendations, diagnostic techniques, treatment, and the vast range of potential presenting symptoms. Just like our patient, who had incontinence and abrupt loss of motor and sensory function in her lower limbs to be diagnosed with spinal cord compression by metastatic FTC. CONCLUSION: This instance emphasizes how crucial it is to consider FTC as a possible differential diagnosis in cases with spinal metastasis, even when there is no known primary thyroid cancer. Prompt diagnosis, comprehensive staging, and multidisciplinary management are crucial in optimizing outcomes.
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spelling pubmed-103694762023-07-27 Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report Njoum, Yumna Abu-Hilal, Lila H. Barghouthi, Duha Alshawwa, Khaled AbuKeshek, Tawfiq Maree, Mohammed Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Follicular thyroid carcinoma (FTC) exhibits the ability to metastasize hematogenously to distant organs. Spinal metastasis is an unusual site for metastasis that even when it does, spinal metastasis manifests late in the course of the disease and is frequently linked to advanced disease and a bad prognosis. Until 2019, the literature only showed 29 cases of FTC with spinal metastasis as the first presenting feature. CASE PRESENTATION: We present a case of a 67-year-old female who presented with an acute onset of severe neurological deficit that ended up bedridden. Magnetic resonance imaging of the spine revealed a spinal lesion causing severe spinal cord compression. Urgent surgical decompression was performed, and the histopathology confirmed metastatic FTC. Subsequent comprehensive evaluation, unveiled a primary thyroid tumor. CLINICAL DISCUSSION: FTC accounts for 1 % of all malignancies, Therefore, regardless of how irrelevant symptoms may appear at first, it is important to understand all risk factors, screening recommendations, diagnostic techniques, treatment, and the vast range of potential presenting symptoms. Just like our patient, who had incontinence and abrupt loss of motor and sensory function in her lower limbs to be diagnosed with spinal cord compression by metastatic FTC. CONCLUSION: This instance emphasizes how crucial it is to consider FTC as a possible differential diagnosis in cases with spinal metastasis, even when there is no known primary thyroid cancer. Prompt diagnosis, comprehensive staging, and multidisciplinary management are crucial in optimizing outcomes. Elsevier 2023-07-21 /pmc/articles/PMC10369476/ /pubmed/37481973 http://dx.doi.org/10.1016/j.ijscr.2023.108541 Text en © 2023 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Njoum, Yumna
Abu-Hilal, Lila H.
Barghouthi, Duha
Alshawwa, Khaled
AbuKeshek, Tawfiq
Maree, Mohammed
Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report
title Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report
title_full Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report
title_fullStr Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report
title_full_unstemmed Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report
title_short Unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: A case report
title_sort unveiling follicular thyroid carcinoma by solitary spinal metastasis causing severe neurological deficit in a 67-year-old female: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369476/
https://www.ncbi.nlm.nih.gov/pubmed/37481973
http://dx.doi.org/10.1016/j.ijscr.2023.108541
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