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Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español

BACKGROUND AND AIM: Since their effectiveness was initially demonstrated, oral corticosteroids (OCS) have been routinely used to treat asthma. We now know that their usage is linked to the development of side effects such osteoporosis and adrenal insufficiency. This is an observational study based o...

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Autores principales: Domínguez-Ortega, Javier, Delgado Romero, Julio, Muñoz Gall, Xavier, Marco, Amparo, Blanco-Aparicio, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369533/
https://www.ncbi.nlm.nih.gov/pubmed/37496970
http://dx.doi.org/10.1016/j.opresp.2022.100202
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author Domínguez-Ortega, Javier
Delgado Romero, Julio
Muñoz Gall, Xavier
Marco, Amparo
Blanco-Aparicio, Marina
author_facet Domínguez-Ortega, Javier
Delgado Romero, Julio
Muñoz Gall, Xavier
Marco, Amparo
Blanco-Aparicio, Marina
author_sort Domínguez-Ortega, Javier
collection PubMed
description BACKGROUND AND AIM: Since their effectiveness was initially demonstrated, oral corticosteroids (OCS) have been routinely used to treat asthma. We now know that their usage is linked to the development of side effects such osteoporosis and adrenal insufficiency. This is an observational study based on Delphi methodology. The questionnaire was divided into 4 sections: OCS generalities, maintenance treatment, short-term treatment, and adverse events. MATERIALS AND METHODS: Two rounds of a 68-item questionnaire were completed by a panel of 48 allergists and pneumologists. RESULTS: Definitions were agreed upon, as was the proper use of OCS in the treatment of severe asthma. The experts agreed that the use of OCS should be minimized as much as possible and that in the event of maintenance treatments, a slow and progressive tapering strategy should be used. They also emphasized the importance of standardizing the technique for measuring the amount of SCG delivered in both cases. CONCLUSIONS: This consensus document attempts to bring together scientifically supported suggestions from specialists in the management of asthma to reduce the use of OCS in Spain.
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spelling pubmed-103695332023-07-26 Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español Domínguez-Ortega, Javier Delgado Romero, Julio Muñoz Gall, Xavier Marco, Amparo Blanco-Aparicio, Marina Open Respir Arch Original BACKGROUND AND AIM: Since their effectiveness was initially demonstrated, oral corticosteroids (OCS) have been routinely used to treat asthma. We now know that their usage is linked to the development of side effects such osteoporosis and adrenal insufficiency. This is an observational study based on Delphi methodology. The questionnaire was divided into 4 sections: OCS generalities, maintenance treatment, short-term treatment, and adverse events. MATERIALS AND METHODS: Two rounds of a 68-item questionnaire were completed by a panel of 48 allergists and pneumologists. RESULTS: Definitions were agreed upon, as was the proper use of OCS in the treatment of severe asthma. The experts agreed that the use of OCS should be minimized as much as possible and that in the event of maintenance treatments, a slow and progressive tapering strategy should be used. They also emphasized the importance of standardizing the technique for measuring the amount of SCG delivered in both cases. CONCLUSIONS: This consensus document attempts to bring together scientifically supported suggestions from specialists in the management of asthma to reduce the use of OCS in Spain. Elsevier 2022-09-06 /pmc/articles/PMC10369533/ /pubmed/37496970 http://dx.doi.org/10.1016/j.opresp.2022.100202 Text en © 2022 Sociedad Española de Neumología y Cirugía Torácica (SEPAR). Published by Elsevier España, S.L.U. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original
Domínguez-Ortega, Javier
Delgado Romero, Julio
Muñoz Gall, Xavier
Marco, Amparo
Blanco-Aparicio, Marina
Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español
title Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español
title_full Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español
title_fullStr Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español
title_full_unstemmed Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español
title_short Uso de glucocorticoides sistémicos para el tratamiento del asma grave: Consenso multidisciplinar español
title_sort uso de glucocorticoides sistémicos para el tratamiento del asma grave: consenso multidisciplinar español
topic Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369533/
https://www.ncbi.nlm.nih.gov/pubmed/37496970
http://dx.doi.org/10.1016/j.opresp.2022.100202
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