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Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C

AIM OF THE STUDY: To analyse the consistency between 2D shear-wave elastography (2D-SWE) stiffness and fibrosis in liver biopsy in patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. The secondary aim of the study was to analyse the consistency between liver stiffne...

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Autores principales: Martonik, Diana, Wandałowicz, Alicja, Supronowicz, Łukasz, Panasiuk, Anatol, Parfieniuk-Kowerda, Anna, Flisiak, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369658/
https://www.ncbi.nlm.nih.gov/pubmed/37502433
http://dx.doi.org/10.5114/ceh.2023.129112
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author Martonik, Diana
Wandałowicz, Alicja
Supronowicz, Łukasz
Panasiuk, Anatol
Parfieniuk-Kowerda, Anna
Flisiak, Robert
author_facet Martonik, Diana
Wandałowicz, Alicja
Supronowicz, Łukasz
Panasiuk, Anatol
Parfieniuk-Kowerda, Anna
Flisiak, Robert
author_sort Martonik, Diana
collection PubMed
description AIM OF THE STUDY: To analyse the consistency between 2D shear-wave elastography (2D-SWE) stiffness and fibrosis in liver biopsy in patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. The secondary aim of the study was to analyse the consistency between liver stiffness in 2D-SWE and transient elastography (TE) measurements in patients with chronic hepatitis B and C. MATERIAL AND METHODS: The study compared the results of hepatic stiffness assessment with 2D-SWE to available past liver biopsy reports in 153 patients with chronic HBV (n = 51) and HCV (n = 102) infection. In 43 patients with both hepatitides HBV (n = 8) and HCV (n = 35) we performed FibroScan on the same day as 2D-SWE. The appropriate statistical tests were applied for the analysis. RESULTS: Stiffness values analysed in the whole studied population showed a significant positive correlation with a stage of liver fibrosis in biopsy (r = 0.555, p < 0.001). If 2D-SWE was carried out within 24 months since liver biopsy the consistency of the results was 96%, and if the period between procedures exceeded 24 months the consistency was 81%. In 43 patients with both 2D-SWE and TE the coherence (r = 0.872, p < 0.001) and consistency (95%) between these two methods were high. CONCLUSIONS: Liver stiffness measured with 2D-SWE showed good consistency with stage of liver fibrosis in liver biopsies, particularly in HCV infected patients, and if the period between procedures did not exceed 24 months.
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spelling pubmed-103696582023-07-27 Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C Martonik, Diana Wandałowicz, Alicja Supronowicz, Łukasz Panasiuk, Anatol Parfieniuk-Kowerda, Anna Flisiak, Robert Clin Exp Hepatol Original Paper AIM OF THE STUDY: To analyse the consistency between 2D shear-wave elastography (2D-SWE) stiffness and fibrosis in liver biopsy in patients with chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. The secondary aim of the study was to analyse the consistency between liver stiffness in 2D-SWE and transient elastography (TE) measurements in patients with chronic hepatitis B and C. MATERIAL AND METHODS: The study compared the results of hepatic stiffness assessment with 2D-SWE to available past liver biopsy reports in 153 patients with chronic HBV (n = 51) and HCV (n = 102) infection. In 43 patients with both hepatitides HBV (n = 8) and HCV (n = 35) we performed FibroScan on the same day as 2D-SWE. The appropriate statistical tests were applied for the analysis. RESULTS: Stiffness values analysed in the whole studied population showed a significant positive correlation with a stage of liver fibrosis in biopsy (r = 0.555, p < 0.001). If 2D-SWE was carried out within 24 months since liver biopsy the consistency of the results was 96%, and if the period between procedures exceeded 24 months the consistency was 81%. In 43 patients with both 2D-SWE and TE the coherence (r = 0.872, p < 0.001) and consistency (95%) between these two methods were high. CONCLUSIONS: Liver stiffness measured with 2D-SWE showed good consistency with stage of liver fibrosis in liver biopsies, particularly in HCV infected patients, and if the period between procedures did not exceed 24 months. Termedia Publishing House 2023-06-30 2023-06 /pmc/articles/PMC10369658/ /pubmed/37502433 http://dx.doi.org/10.5114/ceh.2023.129112 Text en Copyright © 2023 Clinical and Experimental Hepatology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). License (http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/) )
spellingShingle Original Paper
Martonik, Diana
Wandałowicz, Alicja
Supronowicz, Łukasz
Panasiuk, Anatol
Parfieniuk-Kowerda, Anna
Flisiak, Robert
Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C
title Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C
title_full Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C
title_fullStr Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C
title_full_unstemmed Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C
title_short Shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis B and C
title_sort shear-wave elastography for evaluation of hepatic stiffness in chronic viral hepatitis b and c
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369658/
https://www.ncbi.nlm.nih.gov/pubmed/37502433
http://dx.doi.org/10.5114/ceh.2023.129112
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