Cargando…
Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients
Vancomycin-resistant enterococci (VRЕ) are recognized as important hospital pathogens which have become common in patients admitted to the intensive care units (ICUs). The purpose of this study was to evaluate the incidence of and the risk factors for colonization with VRE among ICU patients. A tota...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369701/ https://www.ncbi.nlm.nih.gov/pubmed/37496097 http://dx.doi.org/10.1186/s13099-023-00564-x |
_version_ | 1785077814275342336 |
---|---|
author | Hristova, Preslava M. Marinova-Bulgaranova, Teodora V. Strateva, Tanya V. Trifonov, Stefan V. Hitkova, Hristina Y. |
author_facet | Hristova, Preslava M. Marinova-Bulgaranova, Teodora V. Strateva, Tanya V. Trifonov, Stefan V. Hitkova, Hristina Y. |
author_sort | Hristova, Preslava M. |
collection | PubMed |
description | Vancomycin-resistant enterococci (VRЕ) are recognized as important hospital pathogens which have become common in patients admitted to the intensive care units (ICUs). The purpose of this study was to evaluate the incidence of and the risk factors for colonization with VRE among ICU patients. A total of 91 patients who had duration of hospitalization more than 48 h and without infection caused by VRE or/and other microorganisms in the ICU at University Hospital, Pleven were screened for colonization with VRE. The following data were collected: demographic characteristics, clinical information and antimicrobials use. The statistical analysis was performed using SPSS version 27.0. Colonization with VRE was established in 22 patients and one was carrying two enterococcal species. A total of 23 VRE were isolated. The univariate analysis showed that the postoperative critical cares (p < 0.001), cardiovascular diseases (p = 0.009) and the presence of an endotracheal tube (p = 0.003) were risk factors for colonization with VRE. Also, the postoperative critical cares (p = 0.021) and cardiovascular diseases (p = 0.018) were confirmed as independent risk factor for VRE acquisition by multivariate analysis. The prevalence of VRE colonization among the ICU patients was relatively high (24.2%). Risk factors for acquisition of intestinal VRE were the postoperative cares, cardiovascular diseases and the presence of an endotracheal tube. |
format | Online Article Text |
id | pubmed-10369701 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-103697012023-07-27 Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients Hristova, Preslava M. Marinova-Bulgaranova, Teodora V. Strateva, Tanya V. Trifonov, Stefan V. Hitkova, Hristina Y. Gut Pathog Brief Report Vancomycin-resistant enterococci (VRЕ) are recognized as important hospital pathogens which have become common in patients admitted to the intensive care units (ICUs). The purpose of this study was to evaluate the incidence of and the risk factors for colonization with VRE among ICU patients. A total of 91 patients who had duration of hospitalization more than 48 h and without infection caused by VRE or/and other microorganisms in the ICU at University Hospital, Pleven were screened for colonization with VRE. The following data were collected: demographic characteristics, clinical information and antimicrobials use. The statistical analysis was performed using SPSS version 27.0. Colonization with VRE was established in 22 patients and one was carrying two enterococcal species. A total of 23 VRE were isolated. The univariate analysis showed that the postoperative critical cares (p < 0.001), cardiovascular diseases (p = 0.009) and the presence of an endotracheal tube (p = 0.003) were risk factors for colonization with VRE. Also, the postoperative critical cares (p = 0.021) and cardiovascular diseases (p = 0.018) were confirmed as independent risk factor for VRE acquisition by multivariate analysis. The prevalence of VRE colonization among the ICU patients was relatively high (24.2%). Risk factors for acquisition of intestinal VRE were the postoperative cares, cardiovascular diseases and the presence of an endotracheal tube. BioMed Central 2023-07-26 /pmc/articles/PMC10369701/ /pubmed/37496097 http://dx.doi.org/10.1186/s13099-023-00564-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Brief Report Hristova, Preslava M. Marinova-Bulgaranova, Teodora V. Strateva, Tanya V. Trifonov, Stefan V. Hitkova, Hristina Y. Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients |
title | Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients |
title_full | Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients |
title_fullStr | Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients |
title_full_unstemmed | Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients |
title_short | Risk factors for gut colonization with vancomycin-resistant enterococci among Bulgarian critically ill patients |
title_sort | risk factors for gut colonization with vancomycin-resistant enterococci among bulgarian critically ill patients |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369701/ https://www.ncbi.nlm.nih.gov/pubmed/37496097 http://dx.doi.org/10.1186/s13099-023-00564-x |
work_keys_str_mv | AT hristovapreslavam riskfactorsforgutcolonizationwithvancomycinresistantenterococciamongbulgariancriticallyillpatients AT marinovabulgaranovateodorav riskfactorsforgutcolonizationwithvancomycinresistantenterococciamongbulgariancriticallyillpatients AT stratevatanyav riskfactorsforgutcolonizationwithvancomycinresistantenterococciamongbulgariancriticallyillpatients AT trifonovstefanv riskfactorsforgutcolonizationwithvancomycinresistantenterococciamongbulgariancriticallyillpatients AT hitkovahristinay riskfactorsforgutcolonizationwithvancomycinresistantenterococciamongbulgariancriticallyillpatients |