The impact of vaccine-linked chemotherapy on liver health in a mouse model of chronic Trypanosoma cruzi infection

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BACKGROUND: Chagas disease, chronic infection with Trypanosoma cruzi, mainly manifests as cardiac disease. However, the liver is important for both controlling parasite burdens and metabolizing drugs. Notably, high doses of anti-parasitic drug benznidazole (BNZ) causes liver damage. We previously sh...

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Detalles Bibliográficos
Autores principales: Nguyen, Duc Minh, Poveda, Cristina, Pollet, Jeroen, Gusovsky, Fabian, Bottazzi, Maria Elena, Hotez, Peter J., Jones, Kathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369866/
https://www.ncbi.nlm.nih.gov/pubmed/37503013
http://dx.doi.org/10.1101/2023.07.11.548497
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