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Distinct horizontal transfer mechanisms for type I and type V CRISPR-associated transposons

CRISPR-associated transposons (CASTs) co-opt CRISPR-Cas proteins and Tn7-family transposons for RNA-guided vertical and horizontal transmission. CASTs encode minimal CRISPR arrays but can’t acquire new spacers. Here, we show that CASTs instead co-opt defense-associated CRISPR arrays for horizontal t...

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Detalles Bibliográficos
Autores principales: Hu, Kuang, Chia-Wei, Chou, Wilke, Claus O., Finkelstein, Ilya J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369902/
https://www.ncbi.nlm.nih.gov/pubmed/37502928
http://dx.doi.org/10.1101/2023.03.03.531003