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DNA Origami Tension Sensors (DOTS) to study T cell receptor mechanics at membrane junctions
The T cell receptor (TCR) is thought to be a mechanosensor, meaning that it transmits mechanical force to its antigen and leverages the force to amplify the specificity and magnitude of TCR signaling. The past decade has witnessed the development of molecular probes which have revealed many aspects...
Autores principales: | Hu, Yuesong, Duan, Yuxin, Velusamy, Arventh, Narum, Steven, Rogers, Jhordan, Salaita, Khalid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369911/ https://www.ncbi.nlm.nih.gov/pubmed/37503090 http://dx.doi.org/10.1101/2023.07.09.548279 |
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