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DNA Origami Tension Sensors (DOTS) to study T cell receptor mechanics at membrane junctions

The T cell receptor (TCR) is thought to be a mechanosensor, meaning that it transmits mechanical force to its antigen and leverages the force to amplify the specificity and magnitude of TCR signaling. The past decade has witnessed the development of molecular probes which have revealed many aspects...

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Detalles Bibliográficos
Autores principales: Hu, Yuesong, Duan, Yuxin, Velusamy, Arventh, Narum, Steven, Rogers, Jhordan, Salaita, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369911/
https://www.ncbi.nlm.nih.gov/pubmed/37503090
http://dx.doi.org/10.1101/2023.07.09.548279

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