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Proteome-wide copy-number estimation from transcriptomics

Protein copy numbers constrain systems-level properties of regulatory networks, but absolute proteomic data remain scarce compared to transcriptomics obtained by RNA sequencing. We addressed this persistent gap by relating mRNA to protein statistically using best-available data from quantitative pro...

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Detalles Bibliográficos
Autores principales:	Sweatt, Andrew J., Griffiths, Cameron D., Paudel, B. Bishal, Janes, Kevin A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10369941/ https://www.ncbi.nlm.nih.gov/pubmed/37503057 http://dx.doi.org/10.1101/2023.07.10.548432

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