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Extrusion fountains are hallmarks of chromosome organization emerging upon zygotic genome activation
The first activation of gene expression during development (zygotic genome activation, ZGA) is accompanied by massive changes in chromosome organization. The connection between these two processes remains unknown. Using Hi-C for zebrafish embryos, we found that chromosome folding starts by establish...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370019/ https://www.ncbi.nlm.nih.gov/pubmed/37503128 http://dx.doi.org/10.1101/2023.07.15.549120 |