Strong Positive Selection Biases Identity-By-Descent-Based Inferences of Recent Demography and Population Structure in Plasmodium falciparum

Malaria genomic surveillance often estimates parasite genetic relatedness using metrics such as Identity-By-Decent (IBD). Yet, strong positive selection stemming from antimalarial drug resistance or other interventions may bias IBD-based estimates. In this study, we utilized simulations, a true IBD...

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Detalles Bibliográficos
Autores principales: Guo, Bing, Borda, Victor, Laboulaye, Roland, Spring, Michele D., Wojnarski, Mariusz, Vesely, Brian A., Silva, Joana C., Waters, Norman C., O’Connor, Timothy D., Takala-Harrison, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370022/
https://www.ncbi.nlm.nih.gov/pubmed/37502843
http://dx.doi.org/10.1101/2023.07.14.549114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370022/
https://www.ncbi.nlm.nih.gov/pubmed/37502843
http://dx.doi.org/10.1101/2023.07.14.549114

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