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ACKR3–arrestin2/3 complexes reveal molecular consequences of GRK-dependent barcoding

Atypical chemokine receptor 3 (ACKR3, also known as CXCR7) is a scavenger receptor that regulates extracellular levels of the chemokine CXCL12 to maintain responsiveness of its partner, the G protein-coupled receptor (GPCR), CXCR4. ACKR3 is notable because it does not couple to G proteins and instea...

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Detalles Bibliográficos
Autores principales: Chen, Qiuyan, Schafer, Christopher T., Mukherjee, Somnath, Gustavsson, Martin, Agrawal, Parth, Yao, Xin-Qiu, Kossiakoff, Anthony A., Handel, Tracy M., Tesmer, John J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370059/
https://www.ncbi.nlm.nih.gov/pubmed/37502840
http://dx.doi.org/10.1101/2023.07.18.549504