Cargando…

Smooth muscle-derived adventitial progenitor cells promote key cell type transitions controlling plaque stability in atherosclerosis in a Klf4-dependent manner

We previously established that vascular smooth muscle-derived adventitial progenitor cells (AdvSca1-SM) preferentially differentiate into myofibroblasts and contribute to fibrosis in response to acute vascular injury. However, the role of these progenitor cells in chronic atherosclerosis has not bee...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dubner, Allison M, Lu, Sizhao, Jolly, Austin J, Strand, Keith A, Mutryn, Marie F, Hinthorn, Tyler, Noble, Tysen, Nemenoff, Raphael A, Moulton, Karen S, Majesky, Mark W, Weiser-Evans, Mary CM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370085/ https://www.ncbi.nlm.nih.gov/pubmed/37503181 http://dx.doi.org/10.1101/2023.07.18.549539

Ejemplares similares

Smooth muscle–derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis
por: Lu, Sizhao, et al.
Publicado: (2020)

Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis
por: Jolly, Austin J., et al.
Publicado: (2023)

4369 Reprogramming of vascular smooth muscle cells to multipotent progenitor cells contributes to progression of atherosclerosis
por: Dubner, Allison Milfred, et al.
Publicado: (2020)

Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis
por: Rademakers, Timo, et al.
Publicado: (2017)

An update on clonality: what smooth muscle cell type makes up the atherosclerotic plaque?
por: Schwartz, Stephen M., et al.
Publicado: (2018)

PTEN deficiency promotes pathological vascular remodeling of human coronary arteries
por: Moulton, Karen S., et al.
Publicado: (2018)

ANGPTL4 stabilizes atherosclerotic plaques and modulates the phenotypic transition of vascular smooth muscle cells through KLF4 downregulation
por: Cho, Dong Im, et al.
Publicado: (2023)

Correlation of Adventitial Vasa Vasorum with Intracranial Atherosclerosis: A Postmortem Study
por: Zheng, Lu, et al.
Publicado: (2018)

The Role of KLF2 in the Regulation of Atherosclerosis Development and Potential Use of KLF2-Targeted Therapy
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation
por: Horita, Henrick, et al.
Publicado: (2016)

[(18)F]FDG Uptake in the Aortic Wall Smooth Muscle of Atherosclerotic Plaques in the Simian Atherosclerosis Model
por: Iwaki, Takayuki, et al.
Publicado: (2016)

Versican is differentially regulated in the adventitial and medial layers of human vein grafts
por: Kenagy, Richard D., et al.
Publicado: (2018)

Nicotine exacerbates atherosclerosis and plaque instability via NLRP3 inflammasome activation in vascular smooth muscle cells
por: An, Junqing, et al.
Publicado: (2023)

The Relation between Atherosclerosis Plaque Composition and Plaque Rupture
por: Babaniamansour, Parto, et al.
Publicado: (2020)

Adventitious Joints
por: Tyrie, C. C. Baxter
Publicado: (1894)

Klf4, Klf2, and Zfp148 activate autophagy‐related genes in smooth muscle cells during aortic aneurysm formation
por: Salmon, Morgan, et al.
Publicado: (2019)

Plaque Rupture in Coronary Atherosclerosis Is Associated With Increased Plaque Structural Stress
por: Costopoulos, Charis, et al.
Publicado: (2017)

Pruritic, erythematous, arcuate, and serpiginous smooth plaques
por: Blain, Kimberly, et al.
Publicado: (2021)

Adventitious agents and vaccines.
por: Krause, P R
Publicado: (2001)

miRNA-576 Alleviates the Malignant Progression of Atherosclerosis through Downregulating KLF5
por: Wang, Jing, et al.
Publicado: (2021)

Impaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics
por: Docherty, Craig K., et al.
Publicado: (2018)

Contrast-Enhanced Ultrasound Imaging Quantification of Adventitial Vasa Vasorum in a Rabbit Model of Varying Degrees of Atherosclerosis
por: Li, Xiaoying, et al.
Publicado: (2017)

Plaque Calcification During Atherosclerosis Progression and Regression
por: Shioi, Atsushi, et al.
Publicado: (2018)

Gut Microbiota and Atherosclerosis—Focusing on the Plaque Stability
por: Shen, Xinyi, et al.
Publicado: (2021)

Role of sirtuins in attenuating plaque vulnerability in atherosclerosis
por: Velpuri, Prathosh, et al.
Publicado: (2023)

BMSCs Interactions with Adventitial Fibroblasts Display Smooth Muscle Cell Lineage Potential in Differentiation and Migration That Contributes to Neointimal Formation
por: Wendan, Y., et al.
Publicado: (2016)

RAGE Differentially Altered in vitro Responses in Vascular Smooth Muscle Cells and Adventitial Fibroblasts in Diabetes-Induced Vascular Calcification
por: Kennon, Amber M., et al.
Publicado: (2021)

Senescence in Vascular Smooth Muscle Cells and Atherosclerosis
por: Zha, Yiwen, et al.
Publicado: (2022)

Plaque-targeted, proteolysis-resistant, activatable and MRI-visible nano-GLP-1 receptor agonist targets smooth muscle cell differentiation in atherosclerosis
por: Maiseyeu, Andrei, et al.
Publicado: (2022)

Adventitious Viruses and Smallpox Vaccine
por: Chastel, Claude
Publicado: (2005)

What Makes Adventitious Roots?
por: Gonin, Mathieu, et al.
Publicado: (2019)

Adventitial Cyst of the Popliteal Artery
por: Stagnetto, Margot, et al.
Publicado: (2020)

Atherosclerosis and Atheroma Plaque Rupture: Imaging Modalities in the Visualization of Vasa Vasorum and Atherosclerotic Plaques
por: Sun, Zhonghua
Publicado: (2014)

Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis
por: Beldman, Thijs J., et al.
Publicado: (2017)

Ginsenoside Rb(1) Enhances Plaque Stability and Inhibits Adventitial Vasa Vasorum via the Modulation of miR-33 and PEDF
por: Yang, Xiaoyan, et al.
Publicado: (2021)

KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role in Atherosclerotic Plaque Pathogenesis
por: Shankman, Laura S., et al.
Publicado: (2015)

Norepinephrine acting on adventitial fibroblasts stimulates vascular smooth muscle cell proliferation via promoting small extracellular vesicle release
por: Ye, Chao, et al.
Publicado: (2022)

Paracrine Signals in Calcified Conditioned Media Elicited Differential Responses in Primary Aortic Vascular Smooth Muscle Cells and in Adventitial Fibroblasts
por: Kennon, Amber M., et al.
Publicado: (2023)

MiR-9 promotes the phenotypic switch of vascular smooth muscle cells by targeting KLF5
por: LU, Xiaochun, et al.
Publicado: (2019)

Six Shades of Vascular Smooth Muscle Cells Illuminated by KLF4 (Krüppel-Like Factor 4)
por: Yap, Carmen, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pkvou9vkjb5osc6gaq3bo45f3o