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Allosteric regulation of kinase activity in living cells
The dysregulation of protein kinases is associated with multiple diseases due to the kinases' involvement in a variety of cell signaling pathways. Manipulating protein kinase function, by controlling the active site, is a promising therapeutic and investigative strategy to mitigate and study di...
Autores principales: | Godbole, Shivani, Dokholyan, Nikolay V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370130/ https://www.ncbi.nlm.nih.gov/pubmed/37503033 http://dx.doi.org/10.1101/2023.07.19.549709 |
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