Cargando…

Assessing the impact of autologous neutralizing antibodies on viral rebound in postnatally SHIV-infected ART-treated infant rhesus macaques

While the benefits of early antiretroviral therapy (ART) initiation in perinatally infected infants are well documented, early ART initiation is not always possible in postnatal pediatric HIV infections, which account for the majority of pediatric HIV cases worldwide. The timing of onset of ART init...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mainou, Ellie, Berendam, Stella J, Obregon-Perko, Veronica, Uffman, Emilie A, Phan, Caroline T, Shaw, George M, Bar, Katherine J, Kumar, Mithra R, Fray, Emily J, Siliciano, Janet M, Siliciano, Robert F, Silvestri, Guido, Permar, Sallie R, Fouda, Genevieve G, McCarthy, Janice, Chahroudi, Ann, Conway, Jessica M, Chan, Cliburn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370170/ https://www.ncbi.nlm.nih.gov/pubmed/37502921 http://dx.doi.org/10.1101/2023.07.22.550159

Ejemplares similares

Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4(+) T Cells
por: Obregon-Perko, Veronica, et al.
Publicado: (2020)

Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART
por: Obregon-Perko, Veronica, et al.
Publicado: (2021)

Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques
por: Walker-Sperling, Victoria E. K., et al.
Publicado: (2022)

Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir
por: Kumar, Mithra R., et al.
Publicado: (2023)

Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques
por: Cadena, Anthony M., et al.
Publicado: (2021)

Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation
por: Bricker, Katherine M., et al.
Publicado: (2020)

Vaccine-Induced, High-Magnitude HIV Env-Specific Antibodies with Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques against Oral SHIV Infection
por: Curtis, Alan D., et al.
Publicado: (2022)

Mathematical Modeling of Rhesus Cytomegalovirus Transplacental Transmission in Seronegative Rhesus Macaques
por: Gong, Yishu, et al.
Publicado: (2023)

Persistence of Virus Reservoirs in ART-Treated SHIV-Infected Rhesus Macaques after Autologous Hematopoietic Stem Cell Transplant
por: Mavigner, Maud, et al.
Publicado: (2014)

Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model
por: Goswami, Ria, et al.
Publicado: (2019)

CTL-mediated immunotherapy can suppress SHIV rebound in ART-free macaques
por: Fan, Jin, et al.
Publicado: (2019)

Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques
por: Ventura, John D., et al.
Publicado: (2022)

Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques
por: Podgorski, Rachel M., et al.
Publicado: (2023)

Altered gene expression in asymptomatic SHIV-infected rhesus macaques (Macacca mulatta)
por: Carroll, Erica E, et al.
Publicado: (2006)

Immune Responses and Viral Persistence in Simian/Human Immunodeficiency Virus SHIV.C.CH848-Infected Rhesus Macaques
por: Ziani, Widade, et al.
Publicado: (2021)

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV
por: Marshall, Vickie A., et al.
Publicado: (2018)

Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies
por: Hora, Bhavna, et al.
Publicado: (2023)

Antibody and TLR7 Agonist Delay Viral Rebound in SHIV-Infected Monkeys
por: Borducchi, Erica N., et al.
Publicado: (2018)

Conjugation of HIV-1 envelope to hepatitis B surface antigen alters vaccine responses in rhesus macaques
por: Nettere, Danielle, et al.
Publicado: (2023)

Aikeqing decreases viral loads in SHIV89.6-infected Chinese rhesus macaques
por: Zhang, Gao-Hong, et al.
Publicado: (2016)

Expression of pIgR in the tracheal mucosa of SHIV/SIV-infected rhesus macaques
por: Li, Dong, et al.
Publicado: (2017)

The Brain Retains: Nonhuman Primate Models for Pediatric HIV-1 in the CNS
por: Obregon-Perko, Veronica, et al.
Publicado: (2020)

Potential biomarkers: Predicting post-treatment viral rebound in rhesus macaques
por: Yang, Chenbo, et al.
Publicado: (2023)

Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques
por: Eudailey, Joshua A., et al.
Publicado: (2018)

SHIV-162P3 Infection of Rhesus Macaques Given Maraviroc Gel Vaginally Does Not Involve Resistant Viruses
por: Tsibris, Athe M. N., et al.
Publicado: (2011)

Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV
por: Hill, Alison L., et al.
Publicado: (2016)

Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys.
por: Himes, Jonathon E., et al.
Publicado: (2018)

Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART(®) Molecules
por: Tuyishime, Marina, et al.
Publicado: (2021)

Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV
por: Hill, Alison L., et al.
Publicado: (2017)

Immunoprofiling Correlates of Protection Against SHIV Infection in Adjuvanted HIV-1 Pox-Protein Vaccinated Rhesus Macaques
por: Lu, Pinyi, et al.
Publicado: (2021)

Prophylactic and therapeutic effect of AZT/3TC in RT-SHIV infected Chinese-origin rhesus macaques
por: Wang, Wei, et al.
Publicado: (2014)

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques
por: Wen, Jing, et al.
Publicado: (2021)

Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys
por: Kaur, Amitinder, et al.
Publicado: (2018)

Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth
por: Li, Miranda, et al.
Publicado: (2021)

Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure
por: Berendam, Stella J., et al.
Publicado: (2022)

SIV/SHIV-Zika co-infection does not alter disease pathogenesis in adult non-pregnant rhesus macaque model
por: Bidokhti, Mehdi R. M., et al.
Publicado: (2018)

Target Cell Availability, Rather than Breast Milk Factors, Dictates Mother-to-Infant Transmission of SIV in Sooty Mangabeys and Rhesus Macaques
por: Chahroudi, Ann, et al.
Publicado: (2014)

CD4(+) T Cells Modified by the Endoribonuclease MazF Are Safe and Can Persist in SHIV-infected Rhesus Macaques
por: Saito, Naoki, et al.
Publicado: (2014)

Analysis of Multiply Spliced Transcripts in Lymphoid Tissue Reservoirs of Rhesus Macaques Infected with RT-SHIV during HAART
por: Deere, Jesse D., et al.
Publicado: (2014)

Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques
por: Calenda, Giulia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_gfqgf1bm2l3jo23g45gge3qqe7