Single-nucleus RNA-sequencing reveals oligodendrocytes and their progenitors as vulnerable cell types in prefrontal cortex and anterior cingulate of brains with Parkinson’s disease

Several prior studies have proposed the involvement of various brain regions and cell types in Parkinson’s disease (PD) pathology. Here, we performed snRNA-seq on the prefrontal cortex and anterior cingulate regions from post-mortem control and PD brain tissue. We found a significant association of...

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Detalles Bibliográficos
Autores principales: Dehestani, Mohammad, Blauwendraat, Cornelis, Gasser, Thomas, Bansal, Vikas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370193/
https://www.ncbi.nlm.nih.gov/pubmed/37502982
http://dx.doi.org/10.1101/2023.05.11.540329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370193/
https://www.ncbi.nlm.nih.gov/pubmed/37502982
http://dx.doi.org/10.1101/2023.05.11.540329

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