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Single-nucleus RNA-sequencing reveals oligodendrocytes and their progenitors as vulnerable cell types in prefrontal cortex and anterior cingulate of brains with Parkinson’s disease
Several prior studies have proposed the involvement of various brain regions and cell types in Parkinson’s disease (PD) pathology. Here, we performed snRNA-seq on the prefrontal cortex and anterior cingulate regions from post-mortem control and PD brain tissue. We found a significant association of...
Autores principales: | Dehestani, Mohammad, Blauwendraat, Cornelis, Gasser, Thomas, Bansal, Vikas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370193/ https://www.ncbi.nlm.nih.gov/pubmed/37502982 http://dx.doi.org/10.1101/2023.05.11.540329 |
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