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Identification of the active mechanism of aminoglycoside entry in V. cholerae through characterization of sRNA ctrR, regulating carbohydrate utilization and transport

The possible active entry of aminoglycosides in bacterial cells has been debated since the development of this antibiotic family. Here we report the identification of their active transport mechanism in Vibrio species. We combined genome-wide transcriptional analysis and fitness screens to identify...

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Detalles Bibliográficos
Autores principales: Pierlé, Sebastian A., Lang, Manon, López-Igual, Rocío, Krin, Evelyne, Fourmy, Dominique, Kennedy, Sean P., Val, Marie-Eve, Baharoglu, Zeynep, Mazel, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370196/
https://www.ncbi.nlm.nih.gov/pubmed/37502966
http://dx.doi.org/10.1101/2023.07.19.549712