CAMEL NANOBODY-BASED B7-H3 CAR-T CELLS WITH HIGH EFFICACY AGAINST SOLID TUMORS

BACKGROUND AND SIGNIFICANCE: Chimeric antigen receptor (CAR)-T cell therapy shows promising potency for treating patients with hematological malignancies. However, follow-up data indicate that only 30% to 50% of these patients experience long-term disease control. In solid tumors, the B7-H3 transmem...

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Detalles Bibliográficos
Autores principales: Li, Dan, Wang, Ruixue, Liang, Tianyuzhou, Ren, Hua, Park, Chaelee, Tai, Chin-Hsien, Ni, Weiming, Zhou, Jing, Mackay, Sean, Edmondson, Elijah, Khan, Javed, Croix, Brad St, Ho, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370425/
http://dx.doi.org/10.1093/abt/tbad014.005

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