3H-3000, AN FGFR2B-SPECIFIC MONOCLONAL ANTIBODY, SHOWS SUPERIOR TUMOR KILLING IN VIVO

BACKGROUND AND SIGNIFICANCE: Fibroblast growth factor receptor 2b (FGFR2b), a splice isoform of FGFR2, is found to overexpress across multiple cancers types and promotes dysregulated tyrosine kinase activation, resulting in tumor cell proliferation and unchecked malignancy. Cohort studies reveal FGF...

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Detalles Bibliográficos
Autores principales: Li, You, Zhang, Jianwei, Wang, Ruiqin, Yin, Xueying, Liu, Susan, Lin, Jufang, Hu, Shaojing, Cai, Mingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370428/
http://dx.doi.org/10.1093/abt/tbad014.016

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