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A BIVALENT TIM-3/PD-1 BISPECIFIC ANTIBODY FOR THE TREATMENT OF PD-1 ANTIBODY RESISTANT OR REFRACTORY SOLID TUMORS
BACKGROUND: Immune checkpoint inhibitors (ICI) PD-1/PD-L1 antibody are key drugs for the treatment of cancer. Bispecific antibody is one of the strategies aimed to meet the clinical needs for cancer patients who are resistant to or refractory from ICI treatment. TIM-3, one of the next generation of...
Autores principales: | Luan, Yan, Deng, Hongyuan, Wang, Fengpo, Wang, Cuihui, Zhang, Zhen, Liu, Xun, Abuduwaili, Kahaerjiang, Liu, Jiajian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370444/ http://dx.doi.org/10.1093/abt/tbad014.002 |
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