OVERCOMING TECHNICAL CHALLENGES OF BISPECIFIC AND MULTI-SPECIFIC ANTIBODIES USING NOVEL TECHNOLOGY PLATFORMS

BACKGROUND: Bispecific antibodies (bsAbs) and multispecific antibodies (msAbs) are a growing class of next generation biotherapeutics. However, multiple challenges, such as chain mispairing and developability issues are often associated with these complex modalities. METHODS: WuXi Biologics has esta...

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Detalles Bibliográficos
Autores principales: Xu, Jianqing, Wang, Shuang, Fan, Xinzhao, Wang, George, Gu, Jijie, Nie, Siwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370446/
http://dx.doi.org/10.1093/abt/tbad014.007

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