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TARGETING TREG CELLS BY TNFR2 ANTIBODY INDUCES TUMOR REGRESSION IN VIVO

BACKGROUND: Tumor necrosis factor receptor 2 (TNFR2) is considered an appealing target due to its low-level expression on immune cells, but it could be upregulated on regulatory T cells (Tregs) in the tumor microenvironment which plays key roles in Treg proliferation and function. It has been demons...

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Detalles Bibliográficos
Autores principales:	Yi, Zuoan David, He, Chong, Hso, Yueh-Mei, Strainic, Michael, Yin, Yong, Zhai, Wenwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370447/ http://dx.doi.org/10.1093/abt/tbad014.015

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