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Integrating scRNA and bulk-RNA sequencing develops a cell senescence signature for analyzing tumor heterogeneity in clear cell renal cell carcinoma

INTRODUCTION: Cellular senescence (CS) plays a critical role in cancer development, including clear cell renal cell carcinoma (ccRCC). Traditional RNA sequencing cannot detect precise molecular composition changes within tumors. This study aimed to analyze cellular senescence’s biochemical character...

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Detalles Bibliográficos
Autores principales:	Gong, Qiming, Jiang, Yan, Xiong, Junfeng, Liu, Fahui, Guan, Jikui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370498/ https://www.ncbi.nlm.nih.gov/pubmed/37503331 http://dx.doi.org/10.3389/fimmu.2023.1199002

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