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Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age

PURPOSE: This retrospective research aimed to compare the efficacy of endovascular therapy (EVT) versus microsurgical treatment (MST) for elderly patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS: Elderly (>70 years) patients with aSAH who underwent aneurysm obliteration during 200...

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Autores principales: Akiyama, Ryo, Imamura, Hirotoshi, Tani, Shoichi, Adachi, Hidemitsu, Fukumitsu, Ryu, Sunohara, Tadashi, Omura, Yoshihiro, Funakoshi, Yusuke, Matsui, Yuichi, Sasaki, Natsuhi, Fukuda, Tatsumaru, Horiuchi, Kazufumi, Kajiura, Shinji, Shigeyasu, Masashi, Sakai, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society for Neuroendovascular Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370813/
https://www.ncbi.nlm.nih.gov/pubmed/37502381
http://dx.doi.org/10.5797/jnet.oa.2019-0092
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author Akiyama, Ryo
Imamura, Hirotoshi
Tani, Shoichi
Adachi, Hidemitsu
Fukumitsu, Ryu
Sunohara, Tadashi
Omura, Yoshihiro
Funakoshi, Yusuke
Matsui, Yuichi
Sasaki, Natsuhi
Fukuda, Tatsumaru
Horiuchi, Kazufumi
Kajiura, Shinji
Shigeyasu, Masashi
Sakai, Nobuyuki
author_facet Akiyama, Ryo
Imamura, Hirotoshi
Tani, Shoichi
Adachi, Hidemitsu
Fukumitsu, Ryu
Sunohara, Tadashi
Omura, Yoshihiro
Funakoshi, Yusuke
Matsui, Yuichi
Sasaki, Natsuhi
Fukuda, Tatsumaru
Horiuchi, Kazufumi
Kajiura, Shinji
Shigeyasu, Masashi
Sakai, Nobuyuki
author_sort Akiyama, Ryo
collection PubMed
description PURPOSE: This retrospective research aimed to compare the efficacy of endovascular therapy (EVT) versus microsurgical treatment (MST) for elderly patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS: Elderly (>70 years) patients with aSAH who underwent aneurysm obliteration during 2007–2017 were selected from our hospital database and enrolled in this retrospective study. We reviewed each patient’s background, the severity of the aSAH, and aneurysmal characteristics that compelled EVT or microsurgery treatment and then compared the two treatment groups. A favorable primary outcome was defined by a modified Rankin scale (mRS) score of 0–3 at hospital discharge. The 78 patients formed two cohorts (39 patients each) based on their propensity scores for EVT or MST. We estimated the adjusted odds ratio, followed by a sensitivity analysis of the original 201 patients (118 with EVT and 83 with MST). RESULTS: In the propensity score-matched cohorts, favorable outcomes were observed in 33.3% and 7.7% of patients in the EVT and MST groups, respectively (p = 0.01). Results of the sensitivity analysis were similar to the main results. CONCLUSION: The clinical outcomes for the elderly aSAH patients were better in the EVT group than in MST group.
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spelling pubmed-103708132023-07-27 Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age Akiyama, Ryo Imamura, Hirotoshi Tani, Shoichi Adachi, Hidemitsu Fukumitsu, Ryu Sunohara, Tadashi Omura, Yoshihiro Funakoshi, Yusuke Matsui, Yuichi Sasaki, Natsuhi Fukuda, Tatsumaru Horiuchi, Kazufumi Kajiura, Shinji Shigeyasu, Masashi Sakai, Nobuyuki J Neuroendovasc Ther Original Article PURPOSE: This retrospective research aimed to compare the efficacy of endovascular therapy (EVT) versus microsurgical treatment (MST) for elderly patients with aneurysmal subarachnoid hemorrhage (aSAH). METHODS: Elderly (>70 years) patients with aSAH who underwent aneurysm obliteration during 2007–2017 were selected from our hospital database and enrolled in this retrospective study. We reviewed each patient’s background, the severity of the aSAH, and aneurysmal characteristics that compelled EVT or microsurgery treatment and then compared the two treatment groups. A favorable primary outcome was defined by a modified Rankin scale (mRS) score of 0–3 at hospital discharge. The 78 patients formed two cohorts (39 patients each) based on their propensity scores for EVT or MST. We estimated the adjusted odds ratio, followed by a sensitivity analysis of the original 201 patients (118 with EVT and 83 with MST). RESULTS: In the propensity score-matched cohorts, favorable outcomes were observed in 33.3% and 7.7% of patients in the EVT and MST groups, respectively (p = 0.01). Results of the sensitivity analysis were similar to the main results. CONCLUSION: The clinical outcomes for the elderly aSAH patients were better in the EVT group than in MST group. The Japanese Society for Neuroendovascular Therapy 2019-11-29 2020 /pmc/articles/PMC10370813/ /pubmed/37502381 http://dx.doi.org/10.5797/jnet.oa.2019-0092 Text en ©2020 The Japanese Society for Neuroendovascular Therapy https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives International License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Article
Akiyama, Ryo
Imamura, Hirotoshi
Tani, Shoichi
Adachi, Hidemitsu
Fukumitsu, Ryu
Sunohara, Tadashi
Omura, Yoshihiro
Funakoshi, Yusuke
Matsui, Yuichi
Sasaki, Natsuhi
Fukuda, Tatsumaru
Horiuchi, Kazufumi
Kajiura, Shinji
Shigeyasu, Masashi
Sakai, Nobuyuki
Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age
title Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age
title_full Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age
title_fullStr Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age
title_full_unstemmed Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age
title_short Outcomes of Endovascular Therapy versus Microsurgical Treatment for Aneurysmal Subarachnoid Hemorrhage in Patients ≥70 Years of Age
title_sort outcomes of endovascular therapy versus microsurgical treatment for aneurysmal subarachnoid hemorrhage in patients ≥70 years of age
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370813/
https://www.ncbi.nlm.nih.gov/pubmed/37502381
http://dx.doi.org/10.5797/jnet.oa.2019-0092
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