Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France

We report fatal meningitis in 2 neonates in France caused by Shiga toxin 1–producing Escherichia coli. Virulence factors capsular K1 antigen and salmochelin were present in both strains, potentially representing a new hybrid pathotype. Clinicians should remain aware of emerging pathotypes and design...

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Autores principales: Geslain, Guillaume, Cointe, Aurélie, Bidet, Philippe, Courroux, Céline, Abasse, Soumeth, Mariani, Patricia, Bonacorsi, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370830/
https://www.ncbi.nlm.nih.gov/pubmed/37486718
http://dx.doi.org/10.3201/eid2908.230169
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author Geslain, Guillaume
Cointe, Aurélie
Bidet, Philippe
Courroux, Céline
Abasse, Soumeth
Mariani, Patricia
Bonacorsi, Stéphane
author_facet Geslain, Guillaume
Cointe, Aurélie
Bidet, Philippe
Courroux, Céline
Abasse, Soumeth
Mariani, Patricia
Bonacorsi, Stéphane
author_sort Geslain, Guillaume
collection PubMed
description We report fatal meningitis in 2 neonates in France caused by Shiga toxin 1–producing Escherichia coli. Virulence factors capsular K1 antigen and salmochelin were present in both strains, potentially representing a new hybrid pathotype. Clinicians should remain aware of emerging pathotypes and design therapeutic strategies for neonatal E. coli infections.
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spelling pubmed-103708302023-08-01 Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France Geslain, Guillaume Cointe, Aurélie Bidet, Philippe Courroux, Céline Abasse, Soumeth Mariani, Patricia Bonacorsi, Stéphane Emerg Infect Dis Research Letter We report fatal meningitis in 2 neonates in France caused by Shiga toxin 1–producing Escherichia coli. Virulence factors capsular K1 antigen and salmochelin were present in both strains, potentially representing a new hybrid pathotype. Clinicians should remain aware of emerging pathotypes and design therapeutic strategies for neonatal E. coli infections. Centers for Disease Control and Prevention 2023-08 /pmc/articles/PMC10370830/ /pubmed/37486718 http://dx.doi.org/10.3201/eid2908.230169 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Geslain, Guillaume
Cointe, Aurélie
Bidet, Philippe
Courroux, Céline
Abasse, Soumeth
Mariani, Patricia
Bonacorsi, Stéphane
Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France
title Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France
title_full Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France
title_fullStr Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France
title_full_unstemmed Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France
title_short Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France
title_sort fatal meningitis from shiga toxin–producing escherichia coli in 2 full-term neonates, france
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370830/
https://www.ncbi.nlm.nih.gov/pubmed/37486718
http://dx.doi.org/10.3201/eid2908.230169
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