Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada

We determined correlations between SARS-CoV-2 load in untreated water and COVID-19 cases and patient hospitalizations before the Omicron variant (September 2020–November 2021) at 2 wastewater treatment plants in the Regional Municipality of Peel, Ontario, Canada. Using pre-Omicron correlations, we e...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Lydia, Dhiyebi, Hadi A., Varia, Monali, Atanas, Kyle, Srikanthan, Nivetha, Hayat, Samina, Ikert, Heather, Fuzzen, Meghan, Sing-Judge, Carly, Badlani, Yash, Zeeb, Eli, Bragg, Leslie M., Delatolla, Robert, Giesy, John P., Gilliland, Elaine, Servos, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370834/
https://www.ncbi.nlm.nih.gov/pubmed/37379513
http://dx.doi.org/10.3201/eid2908.221580
_version_ 1785078022387269632
author Cheng, Lydia
Dhiyebi, Hadi A.
Varia, Monali
Atanas, Kyle
Srikanthan, Nivetha
Hayat, Samina
Ikert, Heather
Fuzzen, Meghan
Sing-Judge, Carly
Badlani, Yash
Zeeb, Eli
Bragg, Leslie M.
Delatolla, Robert
Giesy, John P.
Gilliland, Elaine
Servos, Mark R.
author_facet Cheng, Lydia
Dhiyebi, Hadi A.
Varia, Monali
Atanas, Kyle
Srikanthan, Nivetha
Hayat, Samina
Ikert, Heather
Fuzzen, Meghan
Sing-Judge, Carly
Badlani, Yash
Zeeb, Eli
Bragg, Leslie M.
Delatolla, Robert
Giesy, John P.
Gilliland, Elaine
Servos, Mark R.
author_sort Cheng, Lydia
collection PubMed
description We determined correlations between SARS-CoV-2 load in untreated water and COVID-19 cases and patient hospitalizations before the Omicron variant (September 2020–November 2021) at 2 wastewater treatment plants in the Regional Municipality of Peel, Ontario, Canada. Using pre-Omicron correlations, we estimated incident COVID-19 cases during Omicron outbreaks (November 2021–June 2022). The strongest correlation between wastewater SARS-CoV-2 load and COVID-19 cases occurred 1 day after sampling (r = 0.911). The strongest correlation between wastewater load and COVID-19 patient hospitalizations occurred 4 days after sampling (r = 0.819). At the peak of the Omicron BA.2 outbreak in April 2022, reported COVID-19 cases were underestimated 19-fold because of changes in clinical testing. Wastewater data provided information for local decision-making and are a useful component of COVID-19 surveillance systems.
format Online
Article
Text
id pubmed-10370834
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-103708342023-08-01 Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada Cheng, Lydia Dhiyebi, Hadi A. Varia, Monali Atanas, Kyle Srikanthan, Nivetha Hayat, Samina Ikert, Heather Fuzzen, Meghan Sing-Judge, Carly Badlani, Yash Zeeb, Eli Bragg, Leslie M. Delatolla, Robert Giesy, John P. Gilliland, Elaine Servos, Mark R. Emerg Infect Dis Research We determined correlations between SARS-CoV-2 load in untreated water and COVID-19 cases and patient hospitalizations before the Omicron variant (September 2020–November 2021) at 2 wastewater treatment plants in the Regional Municipality of Peel, Ontario, Canada. Using pre-Omicron correlations, we estimated incident COVID-19 cases during Omicron outbreaks (November 2021–June 2022). The strongest correlation between wastewater SARS-CoV-2 load and COVID-19 cases occurred 1 day after sampling (r = 0.911). The strongest correlation between wastewater load and COVID-19 patient hospitalizations occurred 4 days after sampling (r = 0.819). At the peak of the Omicron BA.2 outbreak in April 2022, reported COVID-19 cases were underestimated 19-fold because of changes in clinical testing. Wastewater data provided information for local decision-making and are a useful component of COVID-19 surveillance systems. Centers for Disease Control and Prevention 2023-08 /pmc/articles/PMC10370834/ /pubmed/37379513 http://dx.doi.org/10.3201/eid2908.221580 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Cheng, Lydia
Dhiyebi, Hadi A.
Varia, Monali
Atanas, Kyle
Srikanthan, Nivetha
Hayat, Samina
Ikert, Heather
Fuzzen, Meghan
Sing-Judge, Carly
Badlani, Yash
Zeeb, Eli
Bragg, Leslie M.
Delatolla, Robert
Giesy, John P.
Gilliland, Elaine
Servos, Mark R.
Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada
title Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada
title_full Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada
title_fullStr Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada
title_full_unstemmed Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada
title_short Omicron COVID-19 Case Estimates Based on Previous SARS-CoV-2 Wastewater Load, Regional Municipality of Peel, Ontario, Canada
title_sort omicron covid-19 case estimates based on previous sars-cov-2 wastewater load, regional municipality of peel, ontario, canada
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370834/
https://www.ncbi.nlm.nih.gov/pubmed/37379513
http://dx.doi.org/10.3201/eid2908.221580
work_keys_str_mv AT chenglydia omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT dhiyebihadia omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT variamonali omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT atanaskyle omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT srikanthannivetha omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT hayatsamina omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT ikertheather omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT fuzzenmeghan omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT singjudgecarly omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT badlaniyash omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT zeebeli omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT bragglesliem omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT delatollarobert omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT giesyjohnp omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT gillilandelaine omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada
AT servosmarkr omicroncovid19caseestimatesbasedonprevioussarscov2wastewaterloadregionalmunicipalityofpeelontariocanada

Ejemplares similares