Case of Extensively Drug-Resistant Shigella sonnei Infection, United States

We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-lin...

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Autores principales: Choi, Hosoon, Navarathna, Dhammika H., Harston, Brennon L., Hwang, Munok, Corona, Brandon, San Juan, Ma Rowen, Jinadatha, Chetan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2023
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370867/
https://www.ncbi.nlm.nih.gov/pubmed/37486233
http://dx.doi.org/10.3201/eid2908.230411
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author Choi, Hosoon
Navarathna, Dhammika H.
Harston, Brennon L.
Hwang, Munok
Corona, Brandon
San Juan, Ma Rowen
Jinadatha, Chetan
author_facet Choi, Hosoon
Navarathna, Dhammika H.
Harston, Brennon L.
Hwang, Munok
Corona, Brandon
San Juan, Ma Rowen
Jinadatha, Chetan
author_sort Choi, Hosoon
collection PubMed
description We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-line antimicrobials are not effective against emerging XDR Shigella. Fosfomycin, carbapenems, and tigecycline are potential alternatives.
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spelling pubmed-103708672023-08-01 Case of Extensively Drug-Resistant Shigella sonnei Infection, United States Choi, Hosoon Navarathna, Dhammika H. Harston, Brennon L. Hwang, Munok Corona, Brandon San Juan, Ma Rowen Jinadatha, Chetan Emerg Infect Dis Research Letter We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-line antimicrobials are not effective against emerging XDR Shigella. Fosfomycin, carbapenems, and tigecycline are potential alternatives. Centers for Disease Control and Prevention 2023-08 /pmc/articles/PMC10370867/ /pubmed/37486233 http://dx.doi.org/10.3201/eid2908.230411 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Choi, Hosoon
Navarathna, Dhammika H.
Harston, Brennon L.
Hwang, Munok
Corona, Brandon
San Juan, Ma Rowen
Jinadatha, Chetan
Case of Extensively Drug-Resistant Shigella sonnei Infection, United States
title Case of Extensively Drug-Resistant Shigella sonnei Infection, United States
title_full Case of Extensively Drug-Resistant Shigella sonnei Infection, United States
title_fullStr Case of Extensively Drug-Resistant Shigella sonnei Infection, United States
title_full_unstemmed Case of Extensively Drug-Resistant Shigella sonnei Infection, United States
title_short Case of Extensively Drug-Resistant Shigella sonnei Infection, United States
title_sort case of extensively drug-resistant shigella sonnei infection, united states
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10370867/
https://www.ncbi.nlm.nih.gov/pubmed/37486233
http://dx.doi.org/10.3201/eid2908.230411
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