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Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country

Objective  Reporting our experience of the management and treatment of Idiopathic granulomatous mastitis (IGM) in a low-income country by describing patients characteristics and therapy with emphasis on conservative surgical excision and postoperative care as the cornerstone of treatment. Methods  A...

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Autores principales: Llancari, Pedro Antonio, Ortiz, Antonio, Becerra, Juan, Muñoz, Ricardo, Valeriano, Christiam, Novoa, Rommy Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371069/
https://www.ncbi.nlm.nih.gov/pubmed/37494574
http://dx.doi.org/10.1055/s-0043-1770089
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author Llancari, Pedro Antonio
Ortiz, Antonio
Becerra, Juan
Muñoz, Ricardo
Valeriano, Christiam
Novoa, Rommy Helena
author_facet Llancari, Pedro Antonio
Ortiz, Antonio
Becerra, Juan
Muñoz, Ricardo
Valeriano, Christiam
Novoa, Rommy Helena
author_sort Llancari, Pedro Antonio
collection PubMed
description Objective  Reporting our experience of the management and treatment of Idiopathic granulomatous mastitis (IGM) in a low-income country by describing patients characteristics and therapy with emphasis on conservative surgical excision and postoperative care as the cornerstone of treatment. Methods  A retrospective cohort of women with histopathological diagnosis of IGM from 2014 to 2018 at Instituto Nacional Materno Perinatal in Lima, Peru. Patients' characteristics, clinical presentation, treatment, management, postoperative care, and follow-up were analyzed. Results  Thirty-eight patients with histopathological diagnosis of IGM were identified. Their average age was 35.9 years and 23 (60.5%) reported previous use of hormonal contraceptives. Nine (23.7%) patients had chronic mastitis with previous treatment. The time from the onset of symptoms to the first clinic consult was 5.1 months on average. Twenty-one (55.3%) patients had the lesion in the right breast, with a mean size of 6.9 cm. Conservative surgical excision was performed in all patients. Additionally, 86.8% required corticosteroids and 78.9% were treated with antibiotics. Complete remission was obtained at 141 days on average (range 44 to 292 days). Six (15.8%) women reported ipsilateral recurrence and 5 (13.2%), contralateral. The latency time was 25.5 months on average. Conclusion  The conservative surgical treatment demonstrated and close follow-up made for a high cure rate, but with recurrence similar to that reported in the literature. Use of gloves is an alternative to manage post operative wounds in a low-income country. The most frequent adverse effect was breast surgical scar.
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spelling pubmed-103710692023-07-27 Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country Llancari, Pedro Antonio Ortiz, Antonio Becerra, Juan Muñoz, Ricardo Valeriano, Christiam Novoa, Rommy Helena Rev Bras Ginecol Obstet Objective  Reporting our experience of the management and treatment of Idiopathic granulomatous mastitis (IGM) in a low-income country by describing patients characteristics and therapy with emphasis on conservative surgical excision and postoperative care as the cornerstone of treatment. Methods  A retrospective cohort of women with histopathological diagnosis of IGM from 2014 to 2018 at Instituto Nacional Materno Perinatal in Lima, Peru. Patients' characteristics, clinical presentation, treatment, management, postoperative care, and follow-up were analyzed. Results  Thirty-eight patients with histopathological diagnosis of IGM were identified. Their average age was 35.9 years and 23 (60.5%) reported previous use of hormonal contraceptives. Nine (23.7%) patients had chronic mastitis with previous treatment. The time from the onset of symptoms to the first clinic consult was 5.1 months on average. Twenty-one (55.3%) patients had the lesion in the right breast, with a mean size of 6.9 cm. Conservative surgical excision was performed in all patients. Additionally, 86.8% required corticosteroids and 78.9% were treated with antibiotics. Complete remission was obtained at 141 days on average (range 44 to 292 days). Six (15.8%) women reported ipsilateral recurrence and 5 (13.2%), contralateral. The latency time was 25.5 months on average. Conclusion  The conservative surgical treatment demonstrated and close follow-up made for a high cure rate, but with recurrence similar to that reported in the literature. Use of gloves is an alternative to manage post operative wounds in a low-income country. The most frequent adverse effect was breast surgical scar. Thieme Revinter Publicações Ltda. 2023-07-21 /pmc/articles/PMC10371069/ /pubmed/37494574 http://dx.doi.org/10.1055/s-0043-1770089 Text en Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Llancari, Pedro Antonio
Ortiz, Antonio
Becerra, Juan
Muñoz, Ricardo
Valeriano, Christiam
Novoa, Rommy Helena
Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country
title Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country
title_full Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country
title_fullStr Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country
title_full_unstemmed Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country
title_short Treatment and Management Experience of Idiopathic Granulomatous Mastitis in a Low-income Country
title_sort treatment and management experience of idiopathic granulomatous mastitis in a low-income country
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371069/
https://www.ncbi.nlm.nih.gov/pubmed/37494574
http://dx.doi.org/10.1055/s-0043-1770089
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