Selective Blood Cell Hitchhiking in Whole Blood with Ionic Liquid-Coated PLGA Nanoparticles to Redirect Biodistribution After Intravenous Injection

Less than 5% of intravenously-injected nanoparticles (NPs) reach destined sites in the body due to opsonization and immune-based clearance in vascular circulation. By hitchhiking in situ onto specific blood components post-injection, NPs can selectively target tissue sites for unprecedentedly high d...

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Detalles Bibliográficos
Autores principales: Hamadani, Christine M., Dasanayake, Gaya S., Chism, Claylee M., Gorniak, Meghan E., Monroe, Wake G., Merrell, Anya, Pride, Mercedes C., Heintz, Rebekah, Wong, Karen, Hossain, Mehjabeen, Taylor, George, Edgecomb, Sara X., Jones, Deauntaye, Dhar, Joy, Banka, Alison, Singh, Gagandeep, Vashisth, Priyavrat, Randall, Joh'nis, Darlington, Donovan S., Everett, Jaylon, Jarrett, Ethan, Werfel, Thomas A., Eniola-Adefeso, Omolola, Tanner, Eden E. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371090/
https://www.ncbi.nlm.nih.gov/pubmed/37502854
http://dx.doi.org/10.21203/rs.3.rs-3146716/v1

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