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Hepatic ketogenesis regulates lipid homeostasis via ACSL1-mediated fatty acid partitioning

Liver-derived ketone bodies play a crucial role in fasting energy homeostasis by fueling the brain and peripheral tissues. Ketogenesis also acts as a conduit to remove excess acetyl-CoA generated from fatty acid oxidation and protects against diet-induced hepatic steatosis. Surprisingly, no study ha...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Sadeesh, Mooli, Raja Gopal Reddy, Han, Yerin, Fiorenza, Ericka, Kumar, Suchita, Bello, Fiona, Nallanagulagari, Anoop, Karra, Shreya, Teng, Lihong, Jurczak, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371136/
https://www.ncbi.nlm.nih.gov/pubmed/37503004
http://dx.doi.org/10.21203/rs.3.rs-3147009/v1