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The Role of Morphine-Induced Impairment of Intestinal Epithelial Antibacterial Activity in Dysbiosis and its Impact on the Microbiota-Gut-Brain Axis
Recent evidence suggests that chronic exposure to opioid analgesics such as morphine disrupt the intestinal epithelial layer and cause intestinal dysbiosis. Inhibiting opioid-induced dysbiosis can preclude the development of tolerance to opioid-induced antinociception, suggesting an important role o...
Autores principales: | Muchhala, Karan, Kang, Minho, Koseli, Eda, Poklis, Justin, Xu, Qingguo, Dewey, William, Fettweis, Jennifer, Jimenez, Nicole, Akbarali, Hamid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371156/ https://www.ncbi.nlm.nih.gov/pubmed/37503065 http://dx.doi.org/10.21203/rs.3.rs-3084467/v2 |
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