JP1 normalizes tumor vasculature to suppress metastasis and facilitate drug delivery by inhibiting IL-8

Tumor vascular normalization prevents tumor cells from breaking through the basement membrane and entering the vasculature, thereby inhibiting metastasis initiation. In this study, we report that the antitumor peptide JP1 regulated mitochondrial metabolic reprogramming through AMPK/FOXO3a/UQCRC2 sig...

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Detalles Bibliográficos
Autores principales: Cui, Jiahua, Che, Zhen, Zou, Lu, Chen, Dongyin, Xie, Zhan, Ding, Kun, Jiang, Huning, Li, Aiping, Zhou, Jianwei, Shu, Yongqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371244/
https://www.ncbi.nlm.nih.gov/pubmed/37192004
http://dx.doi.org/10.1172/jci.insight.161675

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