An immunosuppressed microenvironment distinguishes lateral ventricle–contacting glioblastomas

Radiographic contact of glioblastoma (GBM) tumors with the lateral ventricle and adjacent stem cell niche correlates with poor patient prognosis, but the cellular basis of this difference is unclear. Here, we reveal and functionally characterize distinct immune microenvironments that predominate in...

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Detalles Bibliográficos
Autores principales: Bartkowiak, Todd, Lima, Sierra M., Hayes, Madeline J., Mistry, Akshitkumar M., Brockman, Asa A., Sinnaeve, Justine, Leelatian, Nalin, Roe, Caroline E., Mobley, Bret C., Chotai, Silky, Weaver, Kyle D., Thompson, Reid C., Chambless, Lola B., Ihrie, Rebecca A., Irish, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10371245/
https://www.ncbi.nlm.nih.gov/pubmed/37192001
http://dx.doi.org/10.1172/jci.insight.160652

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